(Z)-4-Hydroxy Tamoxifen

Name: (Z)-4-Hydroxy Tamoxifen
Brand: Vaqora Chemicals
SKU: VQ-042357

About (Z)-4-Hydroxy Tamoxifen

(Z)-4-Hydroxy Tamoxifen (CAS 68047-06-3) is a metabolite or degradation product of Tamoxifen offered by Vaqora Chemicals. With the molecular formula C26H29NO2, it has a molar mass of 387.5 g/mol. Systematically, it is named 4-[(Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol. Common synonyms include 4-Hydroxytamoxifen and 4-OHT hydrotamoxifen.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Tamoxifen, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (Z)-4-Hydroxy Tamoxifen in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tamoxifen

View every impurity, metabolite and intermediate we list for Tamoxifen.

Tamoxifen impurities

Specifications & identifiers

Chemical identifiers
Product name	(Z)-4-Hydroxy Tamoxifen
Catalogue No.	VQ-042357
CAS Number	68047-06-3
IUPAC name	4-[(Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
Molecular formula	C₂₆H₂₉NO₂
Molecular weight	387.5 g/mol
Exact mass	387.2198
Grade	Reference Standard
HSN code	38229090
InChIKey	TXUZVZSFRXZGTL-QPLCGJKRSA-N
SMILES	CC/C(=C(\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3
PubChem CID	449459

Physical properties
Physical form	Solid
LogP (XLogP3)	6.8
H-bond donors / acceptors	1 / 3
TPSA	32.7 Å²
Synonyms	4-Hydroxytamoxifen, 4-OHT hydrotamoxifen, 4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol, 4-((Z)-1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol, 4OH-tamoxifen, 4-((1Z)-1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol, 4-((Z)-1-(4-(2-dimethylaminoethyloxy)phenyl)-1-phenylbut-1-en-2-yl) phenol, Afimoxifene, trans-4-Hydroxytamoxifen, 4-Monohydroxytamoxifen, (E/Z)-4-Hydroxytamoxifen

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (Z)-4-Hydroxy Tamoxifen?

The CAS Registry Number of (Z)-4-Hydroxy Tamoxifen is 68047-06-3. It is also known as 4-Hydroxytamoxifen, 4-OHT hydrotamoxifen, 4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol.

What is the molecular formula and molecular weight of (Z)-4-Hydroxy Tamoxifen?

(Z)-4-Hydroxy Tamoxifen has the molecular formula C26H29NO2 and a molecular weight of 387.5 g/mol. Its IUPAC name is 4-[(Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol.

What is (Z)-4-Hydroxy Tamoxifen used for?

(Z)-4-Hydroxy Tamoxifen is supplied as a characterised reference material related to Tamoxifen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (Z)-4-Hydroxy Tamoxifen can I order?

We supply (Z)-4-Hydroxy Tamoxifen in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (Z)-4-Hydroxy Tamoxifen?

Yes. Every lot of (Z)-4-Hydroxy Tamoxifen is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (Z)-4-Hydroxy Tamoxifen be shipped internationally?

Yes. (Z)-4-Hydroxy Tamoxifen is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.