Entacapone WS

Name: Entacapone WS
Brand: Vaqora Chemicals
SKU: VQ-007458

About Entacapone WS

Vaqora Chemicals supplies Entacapone WS, a high-purity reference standard of Entacapone registered under CAS number 130929-57-6. The compound has the formula C14H15N3O5, corresponding to a molecular weight of 305.29 g/mol. Systematically, it is named (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide. Common synonyms include (E)-Entacapone and Comtan.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Entacapone, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Entacapone

View every impurity, metabolite and intermediate we list for Entacapone.

Entacapone impurities

Specifications & identifiers

Chemical identifiers
Product name	Entacapone WS
Catalogue No.	VQ-007458
CAS Number	130929-57-6
Other CAS	1047659-02-8
IUPAC name	(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
Molecular formula	C₁₄H₁₅N₃O₅
Molecular weight	305.29 g/mol
Exact mass	305.1012
Grade	Reference Standard
HSN code	38229090
InChIKey	JRURYQJSLYLRLN-BJMVGYQFSA-N
SMILES	CCN(CC)C(=O)/C(=C/C1=CC(=C(C(=C1)O)O)[N+](=O)[O-])/C#N
PubChem CID	5281081

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 6
TPSA	130 Å²
Synonyms	2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide, (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide, (E)-Entacapone, Comtan, Comtess, Entacapone, Entacom, OR 611, Parkicapone, OR-611, Entacapone teva, Entacapone orion

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 130929-57-6

IP/BP/USP

Entacapone

CAS: 130929-57-6
Formula: C₁₄H₁₅N₃O₅
MW: 305.29 g/mol

VQ-004039

Frequently asked questions

What is the CAS number of Entacapone WS?

The CAS Registry Number of Entacapone WS is 130929-57-6. It is also known as 2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide, (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide, (E)-Entacapone.

What is the molecular formula and molecular weight of Entacapone WS?

Entacapone WS has the molecular formula C14H15N3O5 and a molecular weight of 305.29 g/mol. Its IUPAC name is (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide.

What is Entacapone WS used for?

Entacapone WS is supplied as a characterised reference material related to Entacapone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Entacapone WS can I order?

We supply Entacapone WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Entacapone WS?

Yes. Every lot of Entacapone WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Entacapone WS be shipped internationally?

Yes. Entacapone WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.