Entacapone

Name: Entacapone
Brand: Vaqora Chemicals
SKU: VQ-004039

About Entacapone

Vaqora Chemicals supplies Entacapone (IP/BP/USP grade), a central nervous system API registered under CAS number 130929-57-6. With the molecular formula C14H15N3O5, it has a molar mass of 305.29 g/mol. Systematically, it is named (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide. It is also known as OR-611 or (E)-Entacapone.

It is supplied as a greenish yellow to yellow crystalline powder(Results:Yellow crystalline powder). Store sealed in a dry, well-ventilated location away from incompatible materials. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

This API belongs to our CNS and psychiatric APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. It is used across pharmaceutical manufacturing.

We offer Entacapone in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Entacapone

View every impurity, metabolite and intermediate we list for Entacapone.

Entacapone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Entacapone
Catalogue No.	VQ-004039
CAS Number	130929-57-6
IUPAC name	(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
Molecular formula	C₁₄H₁₅N₃O₅
Molecular weight	305.29 g/mol
Exact mass	305.1012
Grade	IP/BP/USP
HSN code	2933
InChIKey	JRURYQJSLYLRLN-BJMVGYQFSA-N
SMILES	CCN(CC)C(=O)/C(=C/C1=CC(=C(C(=C1)O)O)[N+](=O)[O-])/C#N
PubChem CID	5281081

Physical properties
Physical form	Powder
Appearance	Greenish yellow to yellow crystalline powder(Results:Yellow crystalline powder)
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 6
TPSA	130 Å²
Synonyms	OR-611, (E)-Entacapone, Entacapone teva, Entacapone orion, (2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide, (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide, 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2E)-, (E)-2-cyano-3-(3,4-dihydroxy-5-nitro-phenyl)-N,N-diethyl-prop-2-enamide, N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamide, 2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide, (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide, (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 130929-57-6

Reference Standard

Entacapone WS

CAS: 130929-57-6
Formula: C₁₄H₁₅N₃O₅
MW: 305.29 g/mol

In stock

Frequently asked questions

What is the CAS number of Entacapone?

The CAS Registry Number of Entacapone is 130929-57-6. It is also known as OR-611, (E)-Entacapone, Entacapone teva.

What is the molecular formula and molecular weight of Entacapone?

Entacapone has the molecular formula C14H15N3O5 and a molecular weight of 305.29 g/mol. Its IUPAC name is (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide.

What is Entacapone used for?

Entacapone is supplied as a characterised reference material related to Entacapone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Entacapone can I order?

We supply Entacapone in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Entacapone?

Yes. Every lot of Entacapone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Entacapone be shipped internationally?

Yes. Entacapone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.