Entacapone EP Impurity D

Name: Entacapone EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-022531

About Entacapone EP Impurity D

Entacapone EP Impurity D (CAS 857629-79-9) is a pharmacopeial impurity of Entacapone offered by Vaqora Chemicals. Formula C16H19N3O5, molecular weight 333.34 g/mol. Systematically, it is named (E)-2-cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide. Alternative names: Entacapone EP Impurity B and Entacapone - Impurity D.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Entacapone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Entacapone EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Entacapone

View every impurity, metabolite and intermediate we list for Entacapone.

Entacapone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Entacapone EP Impurity D
Catalogue No.	VQ-022531
CAS Number	857629-79-9
IUPAC name	(E)-2-cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
Molecular formula	C₁₆H₁₉N₃O₅
Molecular weight	333.34 g/mol
Exact mass	333.1325
Grade	Reference Standard
HSN code	38229090
InChIKey	FGJZUPPLPIHQSE-KPKJPENVSA-N
SMILES	CCN(CC)C(=O)/C(=C/C1=CC(=C(C(=C1)OCC)O)[N+](=O)[O-])/C#N
PubChem CID	11484393

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 6
TPSA	119 Å²
Synonyms	Entacapone EP Impurity B, Entacapone - Impurity D, 3-O-ethylentacapone, (2E)-2-cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide, (E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethylacrylamide, (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide, N,N-diethyl-2-cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)acrylamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Entacapone EP Impurity D?

The CAS Registry Number of Entacapone EP Impurity D is 857629-79-9. It is also known as Entacapone EP Impurity B, Entacapone - Impurity D, 3-O-ethylentacapone.

What is the molecular formula and molecular weight of Entacapone EP Impurity D?

Entacapone EP Impurity D has the molecular formula C16H19N3O5 and a molecular weight of 333.34 g/mol. Its IUPAC name is (E)-2-cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide.

What is Entacapone EP Impurity D used for?

Entacapone EP Impurity D is supplied as a characterised reference material related to Entacapone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Entacapone EP Impurity D can I order?

We supply Entacapone EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Entacapone EP Impurity D?

Yes. Every lot of Entacapone EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Entacapone EP Impurity D be shipped internationally?

Yes. Entacapone EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.