Esomeprazole Impurity B

Name: Esomeprazole Impurity B
Brand: Vaqora Chemicals
SKU: VQ-004931

About Esomeprazole Impurity B

Esomeprazole Impurity B (CAS 110374-16-8) is an impurity of Esomeprazole offered by Vaqora Chemicals with a typical assay of 90.12%. Formula C16H17N3O2S, molecular weight 315.4 g/mol. Systematically, it is named 2-[(3,5-dimethyl-2-pyridinyl)methylsulfinyl]-6-methoxy-1H-benzimidazole. Common synonyms include 4-Desmethoxy Omeprazole and Omeprazole EP Impurity B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Esomeprazole, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Esomeprazole Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Esomeprazole

View every impurity, metabolite and intermediate we list for Esomeprazole.

Esomeprazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Esomeprazole Impurity B
Catalogue No.	VQ-004931
CAS Number	110374-16-8
IUPAC name	2-[(3,5-dimethyl-2-pyridinyl)methylsulfinyl]-6-methoxy-1H-benzimidazole
Molecular formula	C₁₆H₁₇N₃O₂S
Molecular weight	315.4 g/mol
Exact mass	315.1041
Grade	Reference Standard
Purity / assay	90.12%
HSN code	38229090
InChIKey	ZMXZYNHJPJEPAE-UHFFFAOYSA-N
SMILES	CC1=CC(=C(N=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC)C
PubChem CID	46781146

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 5
TPSA	87.1 Å²
Synonyms	2-[[(3,5-Dimethyl-2-pyridinyl)methyl]sulfinyl]-6-methoxy-1H-benzimidazole, 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole, 2-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole, 4-Desmethoxy Omeprazole, Omeprazole EP Impurity B, Omeprazole Impurity B, 1H-Benzimidazole, 2-(((3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-6-methoxy-, 2-((RS)-((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole, Omeprazole magnesium impurity B, 2-[(3,5-dimethylpyridin-2-yl)methylsulfinyl]-6-methoxy-1H-benzimidazole, 5-Methoxy-2-[(3,5-dimethyl-2-pyridinyl)-methylsulfinyl]-benzimidazole, (+/-)-2-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P280, P301 + P317, P302 + P352, P321, P330, P332 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Esomeprazole Impurity B?

The CAS Registry Number of Esomeprazole Impurity B is 110374-16-8. It is also known as 2-[[(3,5-Dimethyl-2-pyridinyl)methyl]sulfinyl]-6-methoxy-1H-benzimidazole, 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole, 2-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole.

What is the molecular formula and molecular weight of Esomeprazole Impurity B?

Esomeprazole Impurity B has the molecular formula C16H17N3O2S and a molecular weight of 315.4 g/mol. Its IUPAC name is 2-[(3,5-dimethyl-2-pyridinyl)methylsulfinyl]-6-methoxy-1H-benzimidazole.

What is Esomeprazole Impurity B used for?

Esomeprazole Impurity B is supplied as a characterised reference material related to Esomeprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Esomeprazole Impurity B can I order?

We supply Esomeprazole Impurity B in Reference Standard (90.12%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Esomeprazole Impurity B?

Yes. Every lot of Esomeprazole Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Esomeprazole Impurity B be shipped internationally?

Yes. Esomeprazole Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.