Ethyl (1R,2R)-2-(3,4-difluorophenyl)cycloprop… 1006376-61-9

Name: Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-042521

About Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate

Listed under CAS 1006376-61-9, Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate is an impurity of Ticagrelor available from Vaqora Chemicals. The compound has the formula C12H12F2O2, corresponding to a molecular weight of 226.22 g/mol. Its systematic (IUPAC) name is trans-ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate. Alternative names: CS-B0684.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Ticagrelor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate
Catalogue No.	VQ-042521
CAS Number	1006376-61-9
IUPAC name	trans-ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate
Molecular formula	C₁₂H₁₂F₂O₂
Molecular weight	226.22 g/mol
Exact mass	226.0805
Grade	Reference Standard
HSN code	38229090
InChIKey	WKJJNMWERMSARF-DTWKUNHWSA-N
SMILES	CCOC(=O)[C@@H]1C[C@H]1C2=CC(=C(C=C2)F)F
PubChem CID	57407735

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 4
TPSA	26.3 Å²
Synonyms	Ethyl (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylate, Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate, (1R,2R)-, (1R,2R)-Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate, Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, ethyl ester, (1R,2R)-, (1R,2R)-trans-Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate, (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid ethyl ester, (1R,2R)-Ethyl2-(3,4-difluorophenyl)cyclopropanecarboxylate, CS-B0684, Ethyl trans-2-(3,4-Difluorophenyl)cyclopropanecarboxylate, Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate, trans-, Ethyl(1R,2R)-2-(3,4-difluorophenyl)-1-cyclopropanecarboxylate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate?

The CAS Registry Number of Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate is 1006376-61-9. It is also known as Ethyl (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylate, Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate, (1R,2R)-, (1R,2R)-Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate.

What is the molecular formula and molecular weight of Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate?

Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate has the molecular formula C12H12F2O2 and a molecular weight of 226.22 g/mol. Its IUPAC name is trans-ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate.

What is Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate used for?

Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate can I order?

We supply Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate?

Yes. Every lot of Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate be shipped internationally?

Yes. We export Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.