Hydroxydonepezil

Name: Hydroxydonepezil
Brand: Vaqora Chemicals
SKU: VQ-025371

About Hydroxydonepezil

Hydroxydonepezil (CAS 197010-20-1) is a metabolite or degradation product of Donepezil offered by Vaqora Chemicals. Its molecular formula is C24H29NO4 and its molecular weight is 395.5 g/mol. The IUPAC name is 2-[(1-benzylpiperidin-4-yl)-hydroxymethyl]-5,6-dimethoxy-2,3-dihydroinden-1-one. It is also known as Hydroxy Donepezil (Mixture of Isomer).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Donepezil, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Hydroxydonepezil in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxydonepezil
Catalogue No.	VQ-025371
CAS Number	197010-20-1
IUPAC name	2-[(1-benzylpiperidin-4-yl)-hydroxymethyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
Molecular formula	C₂₄H₂₉NO₄
Molecular weight	395.5 g/mol
Exact mass	395.2097
Grade	Reference Standard
HSN code	38229090
InChIKey	QKRVJLPAJNHQKT-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)CC(C2=O)C(C3CCN(CC3)CC4=CC=CC=C4)O)OC
PubChem CID	16063453

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	1 / 5
TPSA	59 Å²
Synonyms	2-[(1-Benzylpiperidin-4-yl)hydroxymethyl]-5,6-dimethoxyindan-1-one, 2-((1-Benzylpiperidin-4-yl)(hydroxy)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one, Hydroxy Donepezil (Mixture of Isomer), 2-[(1-Benzylpiperidin-4-yl)hydroxymethyl]-5,6-dimethoxyindan-1-one (Hydroxydonepezil), 2-((1-benzyl-piperidin-4-yl)-hydroxy-methyl)-5,6-dimethoxy-indan-1-one, 2-[(1-Benzyl-4-piperidinyl)(hydroxy)methyl]-5,6-dimethoxy-1-indanone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxydonepezil?

The CAS Registry Number of Hydroxydonepezil is 197010-20-1. It is also known as 2-[(1-Benzylpiperidin-4-yl)hydroxymethyl]-5,6-dimethoxyindan-1-one, 2-((1-Benzylpiperidin-4-yl)(hydroxy)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one, Hydroxy Donepezil (Mixture of Isomer).

What is the molecular formula and molecular weight of Hydroxydonepezil?

Hydroxydonepezil has the molecular formula C24H29NO4 and a molecular weight of 395.5 g/mol. Its IUPAC name is 2-[(1-benzylpiperidin-4-yl)-hydroxymethyl]-5,6-dimethoxy-2,3-dihydroinden-1-one.

What is Hydroxydonepezil used for?

Hydroxydonepezil is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxydonepezil can I order?

We supply Hydroxydonepezil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxydonepezil?

Yes. Every lot of Hydroxydonepezil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxydonepezil be shipped internationally?

Yes. We export Hydroxydonepezil worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.