Ibrutinib N1-Oxide

Name: Ibrutinib N1-Oxide
Brand: Vaqora Chemicals
SKU: VQ-026096

About Ibrutinib N1-Oxide

Vaqora Chemicals supplies Ibrutinib N1-Oxide, an impurity of Ibrutinib registered under CAS number 2437254-47-0. Formula C25H24N6O3, molecular weight 456.5 g/mol. Its systematic (IUPAC) name is 1-[(3R)-3-[5-hydroxy-4-imino-3-(4-phenoxyphenyl)pyrazolo[5,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one. Alternative names: Ibrutinib N-oxide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Ibrutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ibrutinib N1-Oxide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ibrutinib N1-Oxide
Catalogue No.	VQ-026096
CAS Number	2437254-47-0
IUPAC name	1-[(3R)-3-[5-hydroxy-4-imino-3-(4-phenoxyphenyl)pyrazolo[5,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
Molecular formula	C₂₅H₂₄N₆O₃
Molecular weight	456.5 g/mol
Exact mass	456.191
Grade	Reference Standard
HSN code	38229090
InChIKey	OIZIQPXPDWYSJD-GOSISDBHSA-N
SMILES	C=CC(=O)N1CCC[C@H](C1)N2C3=C(C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=N)N(C=N3)O
PubChem CID	169442355

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 6
TPSA	107 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ibrutinib N1-Oxide?

The CAS Registry Number of Ibrutinib N1-Oxide is 2437254-47-0. It is also known as Ibrutinib N-oxide.

What is the molecular formula and molecular weight of Ibrutinib N1-Oxide?

Ibrutinib N1-Oxide has the molecular formula C25H24N6O3 and a molecular weight of 456.5 g/mol. Its IUPAC name is 1-[(3R)-3-[5-hydroxy-4-imino-3-(4-phenoxyphenyl)pyrazolo[5,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one.

What is Ibrutinib N1-Oxide used for?

Ibrutinib N1-Oxide is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ibrutinib N1-Oxide can I order?

We supply Ibrutinib N1-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ibrutinib N1-Oxide?

Yes. Every lot of Ibrutinib N1-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ibrutinib N1-Oxide be shipped internationally?

Yes. We export Ibrutinib N1-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.