Imatinib Impurity 1

Name: Imatinib Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-005100

About Imatinib Impurity 1

Imatinib Impurity 1 is an impurity of Imatinib carrying the CAS registry number 106261-48-7, specified at 97.6% purity. With the molecular formula C13H18N2O2, it has a molar mass of 234.29 g/mol. Its systematic (IUPAC) name is 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid. Alternative names: 4-(4-Methylpiperazin-1-ylmethyl)benzoic Acid and 4-(4-Methyl-1-piperazinylmethyl)benzoic Acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Imatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Imatinib Impurity 1 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Imatinib Impurity 1
Catalogue No.	VQ-005100
CAS Number	106261-48-7
IUPAC name	4-[(4-methylpiperazin-1-yl)methyl]benzoic acid
Molecular formula	C₁₃H₁₈N₂O₂
Molecular weight	234.29 g/mol
Exact mass	234.1368
Grade	Reference Standard
Purity / assay	97.6%
HSN code	38229090
InChIKey	ZJUXJQSYXBYFFO-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)O
PubChem CID	4769782

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.2
H-bond donors / acceptors	1 / 4
TPSA	43.8 Å²
Synonyms	4-[(4-Methyl-1-piperazinyl)methyl]benzoic acid, 4-(4-Methylpiperazin-1-ylmethyl)benzoic Acid, 4-(4-Methyl-1-piperazinylmethyl)benzoic Acid, 4-(4-methylpiperazinomethyl)benzoic acid, Benzoic acid, 4-[(4-methyl-1-piperazinyl)methyl]-, 4-((4-Methylpiperazinyl)methyl)benzoic acid, 4-((4-Methyl-1-piperazinyl)methyl)benzoic acid, Benzoic acid, 4-((4-methyl-1-piperazinyl)methyl)-, 4-[(4-methylpiperazinyl)methyl]benzoic acid, M4XAX, 4-(4-methyl-piperazin-1-ylmethyl)-benzoic acid, 4-(4-methylpiperazinyl)methyl benzoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Imatinib Impurity 1?

The CAS Registry Number of Imatinib Impurity 1 is 106261-48-7. It is also known as 4-[(4-Methyl-1-piperazinyl)methyl]benzoic acid, 4-(4-Methylpiperazin-1-ylmethyl)benzoic Acid, 4-(4-Methyl-1-piperazinylmethyl)benzoic Acid.

What is the molecular formula and molecular weight of Imatinib Impurity 1?

Imatinib Impurity 1 has the molecular formula C13H18N2O2 and a molecular weight of 234.29 g/mol. Its IUPAC name is 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid.

What is Imatinib Impurity 1 used for?

Imatinib Impurity 1 is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Imatinib Impurity 1 can I order?

We supply Imatinib Impurity 1 in Reference Standard (97.6%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Imatinib Impurity 1?

Yes. Every lot of Imatinib Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Imatinib Impurity 1 be shipped internationally?

Yes. Imatinib Impurity 1 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.