Imatinib EP Impurity C

Name: Imatinib EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-006433

About Imatinib EP Impurity C

Imatinib EP Impurity C is a pharmacopeial impurity of Imatinib carrying the CAS registry number 404844-02-6. With the molecular formula C28H29N7O, it has a molar mass of 479.6 g/mol. The IUPAC name is N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-(piperazin-1-ylmethyl)benzamide. It is also known as N-Desmethyl Imatinib or N-Desmethyl Gleevec.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Imatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Imatinib EP Impurity C in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Imatinib EP Impurity C
Catalogue No.	VQ-006433
CAS Number	404844-02-6
Other CAS	1820893-54-6, 404844-03-7
IUPAC name	N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-(piperazin-1-ylmethyl)benzamide
Molecular formula	C₂₈H₂₉N₇O
Molecular weight	479.6 g/mol
Exact mass	479.2434
Grade	Reference Standard
HSN code	38229090
InChIKey	BQQYXPHRXIZMDM-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCNCC3)NC4=NC=CC(=N4)C5=CN=CC=C5
PubChem CID	9869737

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	3 / 7
TPSA	95.1 Å²
Synonyms	N-Desmethyl Imatinib, N-Desmethyl Gleevec, Norimatinib, STI 509-00, Imatinib N-Desmethyl Impurity, N-Desmethylimatinib, N Desmethyl imatinib, STI-509-00, CGP-74588 (N-Desmethyl imatinib), N-{3-[4-(3-pyridyl)-2-pyrimidinylamino]-4-tolyl}p-[(1-piperazinyl)methyl]benzamide

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H341Suspected of causing genetic defects
H351Suspected of causing cancer
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Imatinib EP Impurity C?

The CAS Registry Number of Imatinib EP Impurity C is 404844-02-6. It is also known as N-Desmethyl Imatinib, N-Desmethyl Gleevec, Norimatinib.

What is the molecular formula and molecular weight of Imatinib EP Impurity C?

Imatinib EP Impurity C has the molecular formula C28H29N7O and a molecular weight of 479.6 g/mol. Its IUPAC name is N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-(piperazin-1-ylmethyl)benzamide.

What is Imatinib EP Impurity C used for?

Imatinib EP Impurity C is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Imatinib EP Impurity C can I order?

We supply Imatinib EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Imatinib EP Impurity C?

Yes. Every lot of Imatinib EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Imatinib EP Impurity C be shipped internationally?

Yes. Imatinib EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.