Imatinib EP Impurity F

Name: Imatinib EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-006435

About Imatinib EP Impurity F

Imatinib EP Impurity F is a pharmacopeial impurity of Imatinib carrying the CAS registry number 152460-10-1 at a purity of 98%. The compound has the formula C16H15N5, corresponding to a molecular weight of 277.32 g/mol. Its systematic (IUPAC) name is 4-methyl-3-N-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine. Alternative names: Imatinib Diamine Impurity and Imatinib amine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Imatinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Imatinib EP Impurity F in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Imatinib EP Impurity F
Catalogue No.	VQ-006435
CAS Number	152460-10-1
IUPAC name	4-methyl-3-N-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine
Molecular formula	C₁₆H₁₅N₅
Molecular weight	277.32 g/mol
Exact mass	277.1327
Grade	Reference Standard
Purity / assay	98%
HSN code	38229090
InChIKey	QGAIPGVQJVGBIA-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)N)NC2=NC=CC(=N2)C3=CN=CC=C3
PubChem CID	9965429

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 5
TPSA	76.7 Å²
Synonyms	4-Methyl-3-[4-(3-pyridinyl)pyrimidin-2-ylamino]aniline, 4-Methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-benzenediamine, N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine, Imatinib Diamine Impurity, Imatinib amine, 1,3-Benzenediamine, 4-methyl-N3-(4-(3-pyridinyl)-2-pyrimidinyl)-, 1,3-Benzenediamine, 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-, Imatinib amine (USP), 4-Methyl-N3-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine, 4-Methyl-N3-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine, 6-methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine, 2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Imatinib EP Impurity F?

The CAS Registry Number of Imatinib EP Impurity F is 152460-10-1. It is also known as 4-Methyl-3-[4-(3-pyridinyl)pyrimidin-2-ylamino]aniline, 4-Methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-benzenediamine, N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine.

What is the molecular formula and molecular weight of Imatinib EP Impurity F?

Imatinib EP Impurity F has the molecular formula C16H15N5 and a molecular weight of 277.32 g/mol. Its IUPAC name is 4-methyl-3-N-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine.

What is Imatinib EP Impurity F used for?

Imatinib EP Impurity F is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Imatinib EP Impurity F can I order?

We supply Imatinib EP Impurity F in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Imatinib EP Impurity F?

Yes. Every lot of Imatinib EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Imatinib EP Impurity F be shipped internationally?

Yes. Imatinib EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.