Isosorbide-5-mononitrate

Name: Isosorbide-5-mononitrate
Brand: Vaqora Chemicals
SKU: VQ-031278

About Isosorbide-5-mononitrate

Vaqora Chemicals supplies Isosorbide-5-mononitrate, an impurity of Isosorbide registered under CAS number 16051-77-7. With the molecular formula C6H9NO6, it has a molar mass of 191.14 g/mol. Its systematic (IUPAC) name is [(3S,3aR,6R,6aS)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate. Alternative names: Isosorbide Mononitrate and Monosorbitrate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Isosorbide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Isosorbide-5-mononitrate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Isosorbide

View every impurity, metabolite and intermediate we list for Isosorbide.

Isosorbide impurities

Specifications & identifiers

Chemical identifiers
Product name	Isosorbide-5-mononitrate
Catalogue No.	VQ-031278
CAS Number	16051-77-7
IUPAC name	[(3S,3aR,6R,6aS)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate
Molecular formula	C₆H₉NO₆
Molecular weight	191.14 g/mol
Exact mass	191.043
Grade	Reference Standard
HSN code	38229090
InChIKey	YWXYYJSYQOXTPL-SLPGGIOYSA-N
SMILES	C1[C@@H]([C@@H]2[C@H](O1)[C@@H](CO2)O[N+](=O)[O-])O
PubChem CID	27661

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	1 / 6
TPSA	93.7 Å²
Synonyms	Isosorbide Mononitrate, Isosorbide Mononitrate (in lactose Monohydrate), Monosorbitrate, Isosorbide 5-nitrate, Corangin, Duride, Imtrate, Ismexin, Monodur Durules, Mono Corax, 1,4:3,6-Dianhydro-D-glucitol 5-nitrate

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H228Flammable solid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P210, P240, P241, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isosorbide-5-mononitrate?

The CAS Registry Number of Isosorbide-5-mononitrate is 16051-77-7. It is also known as Isosorbide Mononitrate, Isosorbide Mononitrate (in lactose Monohydrate), Monosorbitrate.

What is the molecular formula and molecular weight of Isosorbide-5-mononitrate?

Isosorbide-5-mononitrate has the molecular formula C6H9NO6 and a molecular weight of 191.14 g/mol. Its IUPAC name is [(3S,3aR,6R,6aS)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate.

What is Isosorbide-5-mononitrate used for?

Isosorbide-5-mononitrate is supplied as a characterised reference material related to Isosorbide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isosorbide-5-mononitrate can I order?

We supply Isosorbide-5-mononitrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isosorbide-5-mononitrate?

Yes. Every lot of Isosorbide-5-mononitrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isosorbide-5-mononitrate be shipped internationally?

Yes. Isosorbide-5-mononitrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.