Ketoconazole-d4

Name: Ketoconazole-d4
Brand: Vaqora Chemicals
SKU: VQ-037807

About Ketoconazole-d4

Vaqora Chemicals supplies Ketoconazole-d4, a stable isotope labelled analogue related to Ketoconazole registered under CAS number 1398065-75-2. Formula C26H28Cl2N4O4, molecular weight 535.5 g/mol. It is also known as (+/-)-Ketoconazole-d4 (piperazine-3,3,5,5-d4).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Ketoconazole and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Ketoconazole-d4 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Ketoconazole

View every impurity, metabolite and intermediate we list for Ketoconazole.

Ketoconazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ketoconazole-d4
Catalogue No.	VQ-037807
CAS Number	1398065-75-2
IUPAC name	1-[3,3,5,5-tetradeuterio-4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
Molecular formula	C₂₆H₂₈Cl₂N₄O₄
Molecular weight	535.5 g/mol
Exact mass	534.1739
Grade	Reference Standard
HSN code	38229090
InChIKey	XMAYWYJOQHXEEK-DNYYUWHPSA-N
SMILES	[2H]C1(CN(CC(N1C2=CC=C(C=C2)OC[C@H]3CO[C@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl)([2H])[2H])C(=O)C)[2H]
PubChem CID	124203445

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 6
TPSA	69.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ketoconazole-d4?

The CAS Registry Number of Ketoconazole-d4 is 1398065-75-2. It is also known as (±)-Ketoconazole-d4 (piperazine-3,3,5,5-d4) (cis-isomers), (+/-)-Ketoconazole-d4 (piperazine-3,3,5,5-d4).

What is the molecular formula and molecular weight of Ketoconazole-d4?

Ketoconazole-d4 has the molecular formula C26H28Cl2N4O4 and a molecular weight of 535.5 g/mol. Its IUPAC name is 1-[3,3,5,5-tetradeuterio-4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone.

What is Ketoconazole-d4 used for?

Ketoconazole-d4 is supplied as a characterised reference material related to Ketoconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketoconazole-d4 can I order?

We supply Ketoconazole-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketoconazole-d4?

Yes. Every lot of Ketoconazole-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketoconazole-d4 be shipped internationally?

Yes. We export Ketoconazole-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.