Leuprorelin

Name: Leuprorelin
Brand: Vaqora Chemicals
SKU: VQ-031503

About Leuprorelin

Listed under CAS 53714-56-0, Leuprorelin is a high-purity reference standard of Leuprolide available from Vaqora Chemicals. Formula C59H84N16O12, molecular weight 1209.4 g/mol. It is also known as Leuprolide or Leuproreline.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Leuprolide standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Leuprorelin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Leuprolide

View every impurity, metabolite and intermediate we list for Leuprolide.

Leuprolide impurities

Specifications & identifiers

Chemical identifiers
Product name	Leuprorelin
Catalogue No.	VQ-031503
CAS Number	53714-56-0
IUPAC name	(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular formula	C₅₉H₈₄N₁₆O₁₂
Molecular weight	1209.4 g/mol
Exact mass	1208.6455
Grade	Reference Standard
HSN code	38229090
InChIKey	GFIJNRVAKGFPGQ-LIJARHBVSA-N
SMILES	CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6
PubChem CID	657181

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	15 / 14
TPSA	432 Å²
Synonyms	Leuprolide, Leuproreline, Leuporelin, (-)-leuprolide, Leuprorelin slow release, CKD-841, pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHC2H5, 6-D-Leucine-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor (Pig), Leuprorelin acetate (JAN), Leuprolide acetate (USAN), Leuprolide TFA, Leuprolide acetate salt

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H360May damage fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Leuprorelin?

The CAS Registry Number of Leuprorelin is 53714-56-0. It is also known as Leuprolide, Leuproreline, Leuporelin.

What is the molecular formula and molecular weight of Leuprorelin?

Leuprorelin has the molecular formula C59H84N16O12 and a molecular weight of 1209.4 g/mol.

What is Leuprorelin used for?

Leuprorelin is supplied as a characterised reference material related to Leuprolide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Leuprorelin can I order?

We supply Leuprorelin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Leuprorelin?

Yes. Every lot of Leuprorelin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Leuprorelin be shipped internationally?

Yes. Leuprorelin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.