Leuprorelin Acetate

Name: Leuprorelin Acetate
Brand: Vaqora Chemicals
SKU: VQ-031502

About Leuprorelin Acetate

Listed under CAS 74381-53-6, Leuprorelin Acetate is a high-purity reference standard of Leuprolide available from Vaqora Chemicals. The compound has the formula C61H88N16O14, corresponding to a molecular weight of 1269.4 g/mol. Alternative names: Leuprolide Acetate and Lucrin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Leuprolide standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Leuprorelin Acetate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Leuprolide

View every impurity, metabolite and intermediate we list for Leuprolide.

Leuprolide impurities

Specifications & identifiers

Chemical identifiers
Product name	Leuprorelin Acetate
Catalogue No.	VQ-031502
CAS Number	74381-53-6
IUPAC name	acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular formula	C₆₁H₈₈N₁₆O₁₄
Molecular weight	1269.4 g/mol
Exact mass	1268.6666
Grade	Reference Standard
HSN code	38229090
InChIKey	RGLRXNKKBLIBQS-XNHQSDQCSA-N
SMILES	CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6.CC(=O)O
PubChem CID	657180

Physical properties
Physical form	Solid
H-bond donors / acceptors	16 / 16
TPSA	469 Å²
Synonyms	Leuprolide Acetate, Lucrin, Enantone, Leuplin, Trenantone, Lupron Depot, Abbott-43818, Procrin, TAP-144, Lutrate depot, Uno-Enantone, Leuporelin acetate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H360May damage fertility or the unborn child

Precautionary statements: P203, P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P317, P318, P321, P333 + P317, P342 + P316, P362 + P364, P403, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Leuprorelin Acetate?

The CAS Registry Number of Leuprorelin Acetate is 74381-53-6. It is also known as Leuprolide Acetate, Lucrin, Enantone.

What is the molecular formula and molecular weight of Leuprorelin Acetate?

Leuprorelin Acetate has the molecular formula C61H88N16O14 and a molecular weight of 1269.4 g/mol.

What is Leuprorelin Acetate used for?

Leuprorelin Acetate is supplied as a characterised reference material related to Leuprolide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Leuprorelin Acetate can I order?

We supply Leuprorelin Acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Leuprorelin Acetate?

Yes. Every lot of Leuprorelin Acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Leuprorelin Acetate be shipped internationally?

Yes. Leuprorelin Acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.