Levothyroxine EP Impurity H (Stage -7)

Name: Levothyroxine EP Impurity H (Stage -7)
Brand: Vaqora Chemicals
SKU: VQ-006483

About Levothyroxine EP Impurity H (Stage -7)

Levothyroxine EP Impurity H (Stage -7) is a pharmacopeial impurity of Levothyroxine carrying the CAS registry number 4618-45-5. Its molecular formula is C13H7I3O4 and its molecular weight is 607.9 g/mol. The IUPAC name is 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzoic acid. Common synonyms include 3,5,3'-Triiodothyroformic acid and Triform.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Levothyroxine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Levothyroxine EP Impurity H (Stage -7) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine EP Impurity H (Stage -7)
Catalogue No.	VQ-006483
CAS Number	4618-45-5
IUPAC name	4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzoic acid
Molecular formula	C₁₃H₇I₃O₄
Molecular weight	607.9 g/mol
Exact mass	607.7479
Grade	Reference Standard
HSN code	38229090
InChIKey	UFFBAPYAPOWTEI-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C(=O)O)I)I)O
PubChem CID	20032848

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²
Synonyms	3,5,3'-Triiodothyroformic acid, 3,5-Diiodo-4-(4'-hydroxy-3'-iodophenoxy)benzoic acid, Triform, Triiodothyroformic acid, Levothyroxine EP Impurity H ( Stage -7), 4-(4-Hydroxy-3-iodo-phenoxy)-3,5-diiodo-benzoic acid, 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodobenzoic Acid (3,3',5-Triiodothyroformic Acid)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine EP Impurity H (Stage -7)?

The CAS Registry Number of Levothyroxine EP Impurity H (Stage -7) is 4618-45-5. It is also known as 3,5,3'-Triiodothyroformic acid, 3,5-Diiodo-4-(4'-hydroxy-3'-iodophenoxy)benzoic acid, Triform.

What is the molecular formula and molecular weight of Levothyroxine EP Impurity H (Stage -7)?

Levothyroxine EP Impurity H (Stage -7) has the molecular formula C13H7I3O4 and a molecular weight of 607.9 g/mol. Its IUPAC name is 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzoic acid.

What is Levothyroxine EP Impurity H (Stage -7) used for?

Levothyroxine EP Impurity H (Stage -7) is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine EP Impurity H (Stage -7) can I order?

We supply Levothyroxine EP Impurity H (Stage -7) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine EP Impurity H (Stage -7)?

Yes. Every lot of Levothyroxine EP Impurity H (Stage -7) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine EP Impurity H (Stage -7) be shipped internationally?

Yes. We export Levothyroxine EP Impurity H (Stage -7) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.