Levothyroxine T4-Hydroxyacetic Acid

Name: Levothyroxine T4-Hydroxyacetic Acid
Brand: Vaqora Chemicals
SKU: VQ-013522

About Levothyroxine T4-Hydroxyacetic Acid

Levothyroxine T4-Hydroxyacetic Acid is a process intermediate or related compound of Levothyroxine carrying the CAS registry number 93647-48-4. With the molecular formula C14H8I4O5, it has a molar mass of 763.83 g/mol. Its systematic (IUPAC) name is 2-hydroxy-2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid. Common synonyms include 3,5,3',5'-Tetraiodo Thyromandelic Acid and T4-Hydroxyacetic Acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Levothyroxine, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Levothyroxine T4-Hydroxyacetic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine T4-Hydroxyacetic Acid
Catalogue No.	VQ-013522
CAS Number	93647-48-4
IUPAC name	2-hydroxy-2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid
Molecular formula	C₁₄H₈I₄O₅
Molecular weight	763.83 g/mol
Exact mass	763.6551
Grade	Reference Standard
InChIKey	MORJGZQSVTUXOE-UHFFFAOYSA-N
SMILES	C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C(C(=O)O)O
PubChem CID	24721645

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	3 / 5
TPSA	87 Å²
Synonyms	3,5,3',5'-Tetraiodo Thyromandelic Acid, 2-hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid, 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodomandelic Acid, T4-Hydroxyacetic Acid, α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetic acid, 3,5,3',5'-Tetraiodo Thyromandelic Acid (>85%), 2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid, (+/-)-, Benzeneacetic acid, alpha-hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-, 3,5,3',5' -Tetraiodo thyromandelic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine T4-Hydroxyacetic Acid?

The CAS Registry Number of Levothyroxine T4-Hydroxyacetic Acid is 93647-48-4. It is also known as 3,5,3',5'-Tetraiodo Thyromandelic Acid, 2-hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid, 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodomandelic Acid.

What is the molecular formula and molecular weight of Levothyroxine T4-Hydroxyacetic Acid?

Levothyroxine T4-Hydroxyacetic Acid has the molecular formula C14H8I4O5 and a molecular weight of 763.83 g/mol. Its IUPAC name is 2-hydroxy-2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid.

What is Levothyroxine T4-Hydroxyacetic Acid used for?

Levothyroxine T4-Hydroxyacetic Acid is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine T4-Hydroxyacetic Acid can I order?

We supply Levothyroxine T4-Hydroxyacetic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine T4-Hydroxyacetic Acid?

Yes. Every lot of Levothyroxine T4-Hydroxyacetic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine T4-Hydroxyacetic Acid be shipped internationally?

Yes. We export Levothyroxine T4-Hydroxyacetic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.