Loperamide

Name: Loperamide
Brand: Vaqora Chemicals
SKU: VQ-007551

About Loperamide

Listed under CAS 53179-11-6, Loperamide is a high-purity reference standard of Loperamide available from Vaqora Chemicals. With the molecular formula C29H33ClN2O2, it has a molar mass of 477.0 g/mol. The IUPAC name is 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide. It is also known as ADL 2-1294 or MeSH ID: D008139.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Loperamide standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Loperamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Loperamide

View every impurity, metabolite and intermediate we list for Loperamide.

Loperamide impurities

Specifications & identifiers

Chemical identifiers
Product name	Loperamide
Catalogue No.	VQ-007551
CAS Number	53179-11-6
IUPAC name	4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
Molecular formula	C₂₉H₃₃ClN₂O₂
Molecular weight	477 g/mol
Exact mass	476.2231
Grade	Reference Standard
HSN code	38229090
InChIKey	RDOIQAHITMMDAJ-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4
PubChem CID	3955

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	1 / 3
TPSA	43.8 Å²
Synonyms	4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide, 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide, ADL 2-1294, MeSH ID: D008139, 4-(4-Chlorophenyl)-N,N-dimethyl-alpha,alpha-diphenyl-4-hydroxy-1-piperidinebutanamide, 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, Ioperamide, Maalox Anti-Diarrheal, Loperamide (INN), A1CMV, Apo-Loperamide, Nu-Loperamide

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 53179-11-6

Extra Pure

Loperamide, extra pure

CAS: 53179-11-6
Formula: C₂₉H₃₃ClN₂O₂
MW: 477 g/mol

VQ-046713

Frequently asked questions

What is the CAS number of Loperamide?

The CAS Registry Number of Loperamide is 53179-11-6. It is also known as 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide, 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide, ADL 2-1294.

What is the molecular formula and molecular weight of Loperamide?

Loperamide has the molecular formula C29H33ClN2O2 and a molecular weight of 477 g/mol. Its IUPAC name is 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide.

What is Loperamide used for?

Loperamide is supplied as a characterised reference material related to Loperamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loperamide can I order?

We supply Loperamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loperamide?

Yes. Every lot of Loperamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loperamide be shipped internationally?

Yes. Loperamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.