Loperamide

Name: Loperamide
Brand: Vaqora Chemicals
SKU: VQ-004196

About Loperamide

Loperamide (CAS 34552-83-5) is a gastrointestinal API offered by Vaqora Chemicals (IP/BP/USP grade), specified at 99% purity. With the molecular formula C29H34Cl2N2O2, it has a molar mass of 513.5 g/mol. The IUPAC name is 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide. Hydrochloride. Alternative names: Loperamide hydrochloride and Loperamide HCl.

The product is provided as a powder. Store in a tightly closed container in a cool, dry and well-ventilated place. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our gastrointestinal APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Our customers for this product work in pharmaceutical manufacturing.

Available in 1 kg, 5 kg and 25 kg packs, Loperamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Loperamide

View every impurity, metabolite and intermediate we list for Loperamide.

Loperamide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loperamide
Catalogue No.	VQ-004196
CAS Number	34552-83-5
IUPAC name	4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride
Molecular formula	C₂₉H₃₄Cl₂N₂O₂
Molecular weight	513.5 g/mol
Exact mass	512.1997
Grade	IP/BP/USP
Purity / assay	99%
HSN code	2933
InChIKey	PGYPOBZJRVSMDS-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl
PubChem CID	71420

Physical properties
Physical form	Powder
H-bond donors / acceptors	2 / 3
TPSA	43.8 Å²
Synonyms	Loperamide hydrochloride, Loperamide HCl, Imodium A-D, Imodium A-D EZ chews, Up and up anti diarrheal, Loperamidi hydrochloridum, 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidine butyramide HCl, Imodium classic, Anti Diarrheal, Medique Diamode, Diah-limit, Diarrhoea relief

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 34552-83-5

Reference Standard

Loperamide Hydrochloride

CAS: 34552-83-5
Formula: C₂₉H₃₄Cl₂N₂O₂
MW: 513.5 g/mol

In stock

Frequently asked questions

What is the CAS number of Loperamide?

The CAS Registry Number of Loperamide is 34552-83-5. It is also known as Loperamide hydrochloride, Loperamide HCl, Imodium A-D.

What is the molecular formula and molecular weight of Loperamide?

Loperamide has the molecular formula C29H34Cl2N2O2 and a molecular weight of 513.5 g/mol.

What is Loperamide used for?

Loperamide is supplied as a characterised reference material related to Loperamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loperamide can I order?

We supply Loperamide in IP/BP/USP (99%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loperamide?

Yes. Every lot of Loperamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loperamide be shipped internationally?

Yes. Loperamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.