Loratadine EP Impurity B

Name: Loratadine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-026503

About Loratadine EP Impurity B

Loratadine EP Impurity B (CAS 31251-41-9) is a pharmacopeial impurity of Loratadine offered by Vaqora Chemicals. With the molecular formula C14H10ClNO, it has a molar mass of 243.69 g/mol. Its systematic (IUPAC) name is 13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one. Common synonyms include Loratadine - Impurity B and Loratadine specified impurity B.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Loratadine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Loratadine EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Loratadine

View every impurity, metabolite and intermediate we list for Loratadine.

Loratadine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loratadine EP Impurity B
Catalogue No.	VQ-026503
CAS Number	31251-41-9
IUPAC name	13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one
Molecular formula	C₁₄H₁₀ClNO
Molecular weight	243.69 g/mol
Exact mass	243.0451
Grade	Reference Standard
HSN code	38229090
InChIKey	WMQNOYVVLMIZDV-UHFFFAOYSA-N
SMILES	C1CC2=C(C=CC(=C2)Cl)C(=O)C3=C1C=CC=N3
PubChem CID	9816260

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	0 / 2
TPSA	30 Å²
Synonyms	Loratadine - Impurity B, 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-chloro-5,6-dihydro-11h-benzo(5,6)cyclohepta(1,2-b)pyridin-11-one, Loratadine specified impurity B, 8-Chloro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one, 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-chloro-5,6-dihydro-, 8-Chloro-10,11-dihydro-4-aza-5H-dibenzo[a,d]cycloheptan-5-one, 8-Chloro-10,11-dihydro-4-aza-5H-benzo[A,D] cycloheptan-5-one, 8-Chloro-10,11-dihydro-4-aza-5H-dibenzo-(a,d)cycloheptan-5-one, 8-Chloro-5,6-dihydro-11H-benzo[5.6]cyclohepta[1,2-b]pyridin-11-one, 8-Chloro-10,11-dihydro-4-aza-5H-dibenzo[a,d]cyclohepten-5-one, 8-chloro-5,6-dihydro-11 H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loratadine EP Impurity B?

The CAS Registry Number of Loratadine EP Impurity B is 31251-41-9. It is also known as Loratadine - Impurity B, 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-chloro-5,6-dihydro-11h-benzo(5,6)cyclohepta(1,2-b)pyridin-11-one.

What is the molecular formula and molecular weight of Loratadine EP Impurity B?

Loratadine EP Impurity B has the molecular formula C14H10ClNO and a molecular weight of 243.69 g/mol. Its IUPAC name is 13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one.

What is Loratadine EP Impurity B used for?

Loratadine EP Impurity B is supplied as a characterised reference material related to Loratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loratadine EP Impurity B can I order?

We supply Loratadine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loratadine EP Impurity B?

Yes. Every lot of Loratadine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loratadine EP Impurity B be shipped internationally?

Yes. Loratadine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.