Megestrol Acetate EP Impurity D

Name: Megestrol Acetate EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-023040

About Megestrol Acetate EP Impurity D

Listed under CAS 32634-95-0, Megestrol Acetate EP Impurity D is a pharmacopeial impurity of Progesterone available from Vaqora Chemicals. With the molecular formula C24H32O4, it has a molar mass of 384.5 g/mol. Common synonyms include Medroxyprogesterone Acetate EP Impurity E and Medroxyprogesterone EP Impurity E.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Progesterone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Megestrol Acetate EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Progesterone

View every impurity, metabolite and intermediate we list for Progesterone.

Progesterone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Megestrol Acetate EP Impurity D
Catalogue No.	VQ-023040
CAS Number	32634-95-0
IUPAC name	[(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-6-methylidene-3-oxo-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate
Molecular formula	C₂₄H₃₂O₄
Molecular weight	384.5 g/mol
Exact mass	384.2301
Grade	Reference Standard
HSN code	38229090
InChIKey	YCDZXIYKJHQMIG-GQFGMJRRSA-N
SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=C)C4=CC(=O)CC[C@]34C)C)OC(=O)C
PubChem CID	94436

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	0 / 4
TPSA	60.4 Å²
Synonyms	Medroxyprogesterone Acetate EP Impurity E, Medroxyprogesterone EP Impurity E, Medroxyprogesterone Acetate - Impurity E, Megestrol Acetate - Impurity D, 17-(Acetyloxy)-6-methylenepregn-4-ene-3,20-dione, 17-Acetoxy-6-methylene-4-pregnene-3,20-dione, 6-Methylene Progesterone Acetate, 6-Methylenehydroxyprogesterone Acetate, 6-Methylidene-3,20-dioxopregn-4-en-17-yl Acetate (6-Methylenehydroxyprogesterone Acetate), Methylene substance, 17-Hydroxy-6-methylenepregn-4-ene-3,20-dione Acetate

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P263, P264, P270, P273, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Megestrol Acetate EP Impurity D?

The CAS Registry Number of Megestrol Acetate EP Impurity D is 32634-95-0. It is also known as Medroxyprogesterone Acetate EP Impurity E, Medroxyprogesterone EP Impurity E, Medroxyprogesterone Acetate - Impurity E.

What is the molecular formula and molecular weight of Megestrol Acetate EP Impurity D?

Megestrol Acetate EP Impurity D has the molecular formula C24H32O4 and a molecular weight of 384.5 g/mol. Its IUPAC name is [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-6-methylidene-3-oxo-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate.

What is Megestrol Acetate EP Impurity D used for?

Megestrol Acetate EP Impurity D is supplied as a characterised reference material related to Progesterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Megestrol Acetate EP Impurity D can I order?

We supply Megestrol Acetate EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Megestrol Acetate EP Impurity D?

Yes. Every lot of Megestrol Acetate EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Megestrol Acetate EP Impurity D be shipped internationally?

Yes. Megestrol Acetate EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.