Methotrexate Impurity 2

Name: Methotrexate Impurity 2
Brand: Vaqora Chemicals
SKU: VQ-049074

About Methotrexate Impurity 2

Methotrexate Impurity 2 is an impurity of Methotrexate carrying the CAS registry number 87039-96-1. Formula C12H12ClNO5, molecular weight 285.68 g/mol. The IUPAC name is (2S)-2-[(2-chlorobenzoyl)amino]pentanedioic acid. It is also known as Methotrexate Impurity 47 or (2-chlorobenzoyl)-L-glutamic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Methotrexate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methotrexate Impurity 2 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	Methotrexate Impurity 2
Catalogue No.	VQ-049074
CAS Number	87039-96-1
IUPAC name	(2S)-2-[(2-chlorobenzoyl)amino]pentanedioic acid
Molecular formula	C₁₂H₁₂ClNO₅
Molecular weight	285.68 g/mol
Exact mass	285.0404
Grade	Reference Standard
HSN code	38229090
InChIKey	NECPUMOCNHETCA-VIFPVBQESA-N
SMILES	C1=CC=C(C(=C1)C(=O)N[C@@H](CCC(=O)O)C(=O)O)Cl
PubChem CID	55134947

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	3 / 5
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methotrexate Impurity 2?

The CAS Registry Number of Methotrexate Impurity 2 is 87039-96-1. It is also known as Methotrexate Impurity 47, (2-chlorobenzoyl)-L-glutamic acid.

What is the molecular formula and molecular weight of Methotrexate Impurity 2?

Methotrexate Impurity 2 has the molecular formula C12H12ClNO5 and a molecular weight of 285.68 g/mol. Its IUPAC name is (2S)-2-[(2-chlorobenzoyl)amino]pentanedioic acid.

What is Methotrexate Impurity 2 used for?

Methotrexate Impurity 2 is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methotrexate Impurity 2 can I order?

We supply Methotrexate Impurity 2 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methotrexate Impurity 2?

Yes. Every lot of Methotrexate Impurity 2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methotrexate Impurity 2 be shipped internationally?

Yes. We export Methotrexate Impurity 2 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.