Methotrexate Impurity 21

Name: Methotrexate Impurity 21
Brand: Vaqora Chemicals
SKU: VQ-049075

About Methotrexate Impurity 21

Methotrexate Impurity 21 (CAS 67278-37-9) is an impurity of Methotrexate offered by Vaqora Chemicals. The compound has the formula C14H18N2O5, corresponding to a molecular weight of 294.3 g/mol. Systematically, it is named (2S)-2-[[4-(dimethylamino)benzoyl]amino]pentanedioic acid. Common synonyms include Glutamic acid impurity 8 and (4-(dimethylamino)benzoyl)-L-glutamic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Methotrexate impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methotrexate Impurity 21 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	Methotrexate Impurity 21
Catalogue No.	VQ-049075
CAS Number	67278-37-9
IUPAC name	(2S)-2-[[4-(dimethylamino)benzoyl]amino]pentanedioic acid
Molecular formula	C₁₄H₁₈N₂O₅
Molecular weight	294.3 g/mol
Exact mass	294.1216
Grade	Reference Standard
HSN code	38229090
InChIKey	PONGCTQHPDBBIR-NSHDSACASA-N
SMILES	CN(C)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	61153620

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	3 / 6
TPSA	107 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methotrexate Impurity 21?

The CAS Registry Number of Methotrexate Impurity 21 is 67278-37-9. It is also known as Glutamic acid impurity 8, (4-(dimethylamino)benzoyl)-L-glutamic acid.

What is the molecular formula and molecular weight of Methotrexate Impurity 21?

Methotrexate Impurity 21 has the molecular formula C14H18N2O5 and a molecular weight of 294.3 g/mol. Its IUPAC name is (2S)-2-[[4-(dimethylamino)benzoyl]amino]pentanedioic acid.

What is Methotrexate Impurity 21 used for?

Methotrexate Impurity 21 is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methotrexate Impurity 21 can I order?

We supply Methotrexate Impurity 21 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methotrexate Impurity 21?

Yes. Every lot of Methotrexate Impurity 21 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methotrexate Impurity 21 be shipped internationally?

Yes. We export Methotrexate Impurity 21 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.