Methyl (E)-3-methyl-4-oxobut-2-enoate

Name: Methyl (E)-3-methyl-4-oxobut-2-enoate
Brand: Vaqora Chemicals
SKU: VQ-048718

About Methyl (E)-3-methyl-4-oxobut-2-enoate

Methyl (E)-3-methyl-4-oxobut-2-enoate (CAS 40835-18-5) is an impurity of Isotretinoin offered by Vaqora Chemicals. Its molecular formula is C6H8O3 and its molecular weight is 128.13 g/mol. It is also known as methyl (2E)-3-methyl-4-oxo-2-butenoate or 3-Formylisocrotonic acid methyl ester.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Isotretinoin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Methyl (E)-3-methyl-4-oxobut-2-enoate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl (E)-3-methyl-4-oxobut-2-enoate
Catalogue No.	VQ-048718
CAS Number	40835-18-5
IUPAC name	methyl (E)-3-methyl-4-oxobut-2-enoate
Molecular formula	C₆H₈O₃
Molecular weight	128.13 g/mol
Exact mass	128.0473
Grade	Reference Standard
HSN code	38229090
InChIKey	MQEABLCNUISMMX-HWKANZROSA-N
SMILES	C/C(=C\C(=O)OC)/C=O
PubChem CID	10953519

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	0 / 3
TPSA	43.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl (E)-3-methyl-4-oxobut-2-enoate?

The CAS Registry Number of Methyl (E)-3-methyl-4-oxobut-2-enoate is 40835-18-5. It is also known as methyl (2E)-3-methyl-4-oxo-2-butenoate, 3-Formylisocrotonic acid methyl ester, (E)-Methyl 3-methyl-4-oxobut-2-enoate.

What is the molecular formula and molecular weight of Methyl (E)-3-methyl-4-oxobut-2-enoate?

Methyl (E)-3-methyl-4-oxobut-2-enoate has the molecular formula C6H8O3 and a molecular weight of 128.13 g/mol. Its IUPAC name is methyl (E)-3-methyl-4-oxobut-2-enoate.

What is Methyl (E)-3-methyl-4-oxobut-2-enoate used for?

Methyl (E)-3-methyl-4-oxobut-2-enoate is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl (E)-3-methyl-4-oxobut-2-enoate can I order?

We supply Methyl (E)-3-methyl-4-oxobut-2-enoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl (E)-3-methyl-4-oxobut-2-enoate?

Yes. Every lot of Methyl (E)-3-methyl-4-oxobut-2-enoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl (E)-3-methyl-4-oxobut-2-enoate be shipped internationally?

Yes. We export Methyl (E)-3-methyl-4-oxobut-2-enoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.