N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine (CAS 231278-20-9) chemical structure

VAQORA

API ImpuritiesReference StandardAvailable on request

N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine

Name: N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine
Brand: Vaqora Chemicals
SKU: VQ-031446

Synonyms: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine · 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo- · 4-Quinazolinamine, N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-iodo- · N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-iodo-4-quinazolinamine

CAS No.231278-20-9

FormulaC₂₁H₁₄ClFIN₃O

Mol. weight505.70

Catalogue No.VQ-031446

PurityReference Standard

HSN38229090

N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine (CAS 231278-20-9) – Lapatinib impurity standard. C21H14ClFIN3O, MW 505.7. COA included.

Pack sizesPrice on quotation · bulk available

10 mg

25 mg

50 mg

100 mg

Bulk / custom pack · kg to MT

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Batch COA with every lot

16-section GHS SDS

Export to 120+ countries

DG-compliant packing

About N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine

Vaqora Chemicals supplies N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine, an impurity of Lapatinib registered under CAS number 231278-20-9. With the molecular formula C21H14ClFIN3O, it has a molar mass of 505.7 g/mol. The IUPAC name is N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodoquinazolin-4-amine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Lapatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lapatinib

View every impurity, metabolite and intermediate we list for Lapatinib.

Lapatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine
Catalogue No.	VQ-031446
CAS Number	231278-20-9
IUPAC name	N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodoquinazolin-4-amine
Molecular formula	C₂₁H₁₄ClFIN₃O
Molecular weight	505.7 g/mol
Exact mass	504.9854
Grade	Reference Standard
HSN code	38229090
InChIKey	UHFPFDMMKYQMLC-UHFFFAOYSA-N
SMILES	C1=CC(=CC(=C1)F)COC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)I)Cl
PubChem CID	10174519

Physical properties
Physical form	Solid
LogP (XLogP3)	6.3
H-bond donors / acceptors	1 / 5
TPSA	47 Å²
Synonyms	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine, 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-, 4-Quinazolinamine, N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-iodo-, N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-iodo-4-quinazolinamine, N-{3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-iodoquinazolin-4-amine, 6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline, 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline

Safety & hazard information (GHS)

Hazard statements

H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P273, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine?

The CAS Registry Number of N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine is 231278-20-9. It is also known as N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine, 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-, 4-Quinazolinamine, N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-iodo-.

What is the molecular formula and molecular weight of N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine?

N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine has the molecular formula C21H14ClFIN3O and a molecular weight of 505.7 g/mol. Its IUPAC name is N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodoquinazolin-4-amine.

What is N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine used for?

N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine is supplied as a characterised reference material related to Lapatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine can I order?

We supply N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine?

Yes. Every lot of N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine be shipped internationally?

Yes. We export N-{3-Chloro-4-[(3-fluorobenzyl) oxy] phenyl}- 6-iodoquinazolin-4-amine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.