N-De[2-(methylsulfonyl)ethyl] Lapatinib

Name: N-De[2-(methylsulfonyl)ethyl] Lapatinib
Brand: Vaqora Chemicals
SKU: VQ-026365

About N-De[2-(methylsulfonyl)ethyl] Lapatinib

Listed under CAS 697299-82-4, N-De[2-(methylsulfonyl)ethyl] Lapatinib is an impurity of Lapatinib available from Vaqora Chemicals. The compound has the formula C26H20ClFN4O2, corresponding to a molecular weight of 474.9 g/mol. Systematically, it is named 6-[5-(aminomethyl)furan-2-yl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine. Alternative names: Lapatinib metabolite M4 [DMD] and Lapatinib metabolite M2 [MOLPHARM].

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Lapatinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lapatinib

View every impurity, metabolite and intermediate we list for Lapatinib.

Lapatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-De[2-(methylsulfonyl)ethyl] Lapatinib
Catalogue No.	VQ-026365
CAS Number	697299-82-4
IUPAC name	6-[5-(aminomethyl)furan-2-yl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine
Molecular formula	C₂₆H₂₀ClFN₄O₂
Molecular weight	474.9 g/mol
Exact mass	474.1259
Grade	Reference Standard
HSN code	38229090
InChIKey	NQHFMDSFFGTFSK-UHFFFAOYSA-N
SMILES	C1=CC(=CC(=C1)F)COC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)C5=CC=C(O5)CN)Cl
PubChem CID	21952026

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	2 / 7
TPSA	86.2 Å²
Synonyms	Lapatinib metabolite M4 [DMD], Lapatinib metabolite M2 [MOLPHARM], (6-(5-Aminomethylfuran-2-yl)quinazolin-4-yl)(3-chloro-4-(3-fluorobenzyloxy)phenyl)amine, 6-(5-(Aminomethyl)furan-2-yl)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine, [6-(5-Aminomethylfuran-2-yl)quinazoli n-4-yl][3-chloro-4-(3-fluorobenzyloxy)phenyl]amine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-De[2-(methylsulfonyl)ethyl] Lapatinib?

The CAS Registry Number of N-De[2-(methylsulfonyl)ethyl] Lapatinib is 697299-82-4. It is also known as Lapatinib metabolite M4 [DMD], Lapatinib metabolite M2 [MOLPHARM], (6-(5-Aminomethylfuran-2-yl)quinazolin-4-yl)(3-chloro-4-(3-fluorobenzyloxy)phenyl)amine.

What is the molecular formula and molecular weight of N-De[2-(methylsulfonyl)ethyl] Lapatinib?

N-De[2-(methylsulfonyl)ethyl] Lapatinib has the molecular formula C26H20ClFN4O2 and a molecular weight of 474.9 g/mol. Its IUPAC name is 6-[5-(aminomethyl)furan-2-yl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine.

What is N-De[2-(methylsulfonyl)ethyl] Lapatinib used for?

N-De[2-(methylsulfonyl)ethyl] Lapatinib is supplied as a characterised reference material related to Lapatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-De[2-(methylsulfonyl)ethyl] Lapatinib can I order?

We supply N-De[2-(methylsulfonyl)ethyl] Lapatinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-De[2-(methylsulfonyl)ethyl] Lapatinib?

Yes. Every lot of N-De[2-(methylsulfonyl)ethyl] Lapatinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-De[2-(methylsulfonyl)ethyl] Lapatinib be shipped internationally?

Yes. We export N-De[2-(methylsulfonyl)ethyl] Lapatinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.