N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinaz… 2226537-61-5

Name: N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
Brand: Vaqora Chemicals
SKU: VQ-035634

About N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is an impurity of Afatinib carrying the CAS registry number 2226537-61-5. Formula C14H7F3N4O2, molecular weight 320.23 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Afatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Afatinib

View every impurity, metabolite and intermediate we list for Afatinib.

Afatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
Catalogue No.	VQ-035634
CAS Number	2226537-61-5
IUPAC name	N-(3,4-difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
Molecular formula	C₁₄H₇F₃N₄O₂
Molecular weight	320.23 g/mol
Exact mass	320.0521
Grade	Reference Standard
HSN code	38229090
InChIKey	DZRYHCITHKPDFS-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1NC2=NC=NC3=CC(=C(C=C32)[N+](=O)[O-])F)F)F
PubChem CID	163197479

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	1 / 8
TPSA	83.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine?

The CAS Registry Number of N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is 2226537-61-5.

What is the molecular formula and molecular weight of N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine?

N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine has the molecular formula C14H7F3N4O2 and a molecular weight of 320.23 g/mol. Its IUPAC name is N-(3,4-difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine.

What is N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine used for?

N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is supplied as a characterised reference material related to Afatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine can I order?

We supply N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine?

Yes. Every lot of N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine be shipped internationally?

Yes. We export N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.