N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5… 2300968-87-8

Name: N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide
Brand: Vaqora Chemicals
SKU: VQ-038240

About N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide

Vaqora Chemicals supplies N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide, an impurity of Macitentan registered under CAS number 2300968-87-8. The compound has the formula C19H21BrN6O4S, corresponding to a molecular weight of 509.4 g/mol. Its systematic (IUPAC) name is 6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-phenyl-N-(propylsulfamoyl)pyrimidin-4-amine. Common synonyms include 5-(Desbromophenyl)-5-Phenyl-Macitentan.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Macitentan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide
Catalogue No.	VQ-038240
CAS Number	2300968-87-8
IUPAC name	6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-phenyl-N-(propylsulfamoyl)pyrimidin-4-amine
Molecular formula	C₁₉H₂₁BrN₆O₄S
Molecular weight	509.4 g/mol
Exact mass	508.0528
Grade	Reference Standard
HSN code	38229090
InChIKey	KLZRILKWXHPQRA-UHFFFAOYSA-N
SMILES	CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=CC=C3
PubChem CID	168010560

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 10
TPSA	137 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide?

The CAS Registry Number of N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide is 2300968-87-8. It is also known as 5-(Desbromophenyl)-5-Phenyl-Macitentan.

What is the molecular formula and molecular weight of N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide?

N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide has the molecular formula C19H21BrN6O4S and a molecular weight of 509.4 g/mol. Its IUPAC name is 6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-phenyl-N-(propylsulfamoyl)pyrimidin-4-amine.

What is N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide used for?

N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide can I order?

We supply N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide?

Yes. Every lot of N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide be shipped internationally?

Yes. We export N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.