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VAQORACHEMICALS
Impurity reference standards

Macitentan impurities & reference standards

Characterised Macitentan impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.

37reference materials
1nitrosamine impurities
2isotope-labelled
COAHPLC · NMR · MS on request
Reference Standard
Aprocitentan chemical structure
Aprocitentan
CAS
1103522-45-7
Formula
C16H14Br2N6O4S
MW
546.2 g/mol
VQ-023020
Reference Standard
Aprocitentan-d4 chemical structure
Aprocitentan-d4
CAS
2748196-51-0
Formula
C16H14Br2N6O4S
MW
550.2 g/mol
VQ-035510
Reference Standard
Macitentan chemical structure
Macitentan
CAS
441798-33-0
Formula
C19H20Br2N6O4S
MW
588.3 g/mol
VQ-026547
Reference Standard
Macitentan-d4 chemical structure
Macitentan-d4
CAS
1258428-05-5
Formula
C19H20Br2N6O4S
MW
592.3 g/mol
VQ-038241

FAQs — Macitentan impurities

Which Macitentan impurities do you supply?

We list 37 Macitentan-related reference materials, including process impurities, degradation products, nitrosamine impurities, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.

What are Macitentan impurity standards used for?

They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).

Can you synthesise a Macitentan impurity that is not listed?

Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.

Request Macitentan impurity standards

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