N-Acetyl-L-Thyroxine Impurity

Name: N-Acetyl-L-Thyroxine Impurity
Brand: Vaqora Chemicals
SKU: VQ-005307

About N-Acetyl-L-Thyroxine Impurity

N-Acetyl-L-Thyroxine Impurity (CAS 26041-51-0) is an impurity of Levothyroxine offered by Vaqora Chemicals. With the molecular formula C17H13I4NO5, it has a molar mass of 818.91 g/mol. Systematically, it is named (2S)-2-acetamido-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid. It is also known as N-Acetyl-L-Thyroxine or N-Acetylthyroxine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Levothyroxine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Acetyl-L-Thyroxine Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Acetyl-L-Thyroxine Impurity
Catalogue No.	VQ-005307
CAS Number	26041-51-0
IUPAC name	(2S)-2-acetamido-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
Molecular formula	C₁₇H₁₃I₄NO₅
Molecular weight	818.91 g/mol
Exact mass	818.6973
Grade	Reference Standard
HSN code	38229090
InChIKey	NERGVJCCFAPEMR-AWEZNQCLSA-N
SMILES	CC(=O)N[C@@H](CC1=CC(=C(C(=C1)I)OC2=CC(=C(C(=C2)I)O)I)I)C(=O)O
PubChem CID	20638380

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	3 / 5
TPSA	95.9 Å²
Synonyms	(S)-2-Acetamido-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid, N-Acetyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine, N-Acetyl-L-Thyroxine, N-Acetylthyroxine, Levothyroxine N-Acetyl Impurity, N-Acetyl-T4, Thyroxine, N-acetyl-, L-, L-Tyrosine, N-acetyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, Levothyroxine sodium impurity, N-acetyl-t4-(USP), N-Acetyl L-Thyroxine, N-Acetyl-L-Thyroxine (N-Acetyllevothyroxine), Acetylthyroxin

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Acetyl-L-Thyroxine Impurity?

The CAS Registry Number of N-Acetyl-L-Thyroxine Impurity is 26041-51-0. It is also known as (S)-2-Acetamido-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid, N-Acetyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine, N-Acetyl-L-Thyroxine.

What is the molecular formula and molecular weight of N-Acetyl-L-Thyroxine Impurity?

N-Acetyl-L-Thyroxine Impurity has the molecular formula C17H13I4NO5 and a molecular weight of 818.91 g/mol. Its IUPAC name is (2S)-2-acetamido-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid.

What is N-Acetyl-L-Thyroxine Impurity used for?

N-Acetyl-L-Thyroxine Impurity is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Acetyl-L-Thyroxine Impurity can I order?

We supply N-Acetyl-L-Thyroxine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Acetyl-L-Thyroxine Impurity?

Yes. Every lot of N-Acetyl-L-Thyroxine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Acetyl-L-Thyroxine Impurity be shipped internationally?

Yes. We export N-Acetyl-L-Thyroxine Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.