O-De(3-fluorobenzyl) Lapatinib

Name: O-De(3-fluorobenzyl) Lapatinib
Brand: Vaqora Chemicals
SKU: VQ-022929

About O-De(3-fluorobenzyl) Lapatinib

O-De(3-fluorobenzyl) Lapatinib is an impurity of Lapatinib carrying the CAS registry number 1268997-70-1. With the molecular formula C22H21ClN4O4S, it has a molar mass of 472.9 g/mol. Its systematic (IUPAC) name is 2-chloro-4-[[6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-yl]amino]phenol. It is also known as Lapatinib metabolite M1.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Lapatinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lapatinib

View every impurity, metabolite and intermediate we list for Lapatinib.

Lapatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	O-De(3-fluorobenzyl) Lapatinib
Catalogue No.	VQ-022929
CAS Number	1268997-70-1
IUPAC name	2-chloro-4-[[6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-yl]amino]phenol
Molecular formula	C₂₂H₂₁ClN₄O₄S
Molecular weight	472.9 g/mol
Exact mass	472.0972
Grade	Reference Standard
HSN code	38229090
InChIKey	SVTCWAMLLWYBEI-UHFFFAOYSA-N
SMILES	CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)O)Cl
PubChem CID	71315271

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	3 / 8
TPSA	126 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-De(3-fluorobenzyl) Lapatinib?

The CAS Registry Number of O-De(3-fluorobenzyl) Lapatinib is 1268997-70-1. It is also known as Lapatinib metabolite M1.

What is the molecular formula and molecular weight of O-De(3-fluorobenzyl) Lapatinib?

O-De(3-fluorobenzyl) Lapatinib has the molecular formula C22H21ClN4O4S and a molecular weight of 472.9 g/mol. Its IUPAC name is 2-chloro-4-[[6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-yl]amino]phenol.

What is O-De(3-fluorobenzyl) Lapatinib used for?

O-De(3-fluorobenzyl) Lapatinib is supplied as a characterised reference material related to Lapatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-De(3-fluorobenzyl) Lapatinib can I order?

We supply O-De(3-fluorobenzyl) Lapatinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-De(3-fluorobenzyl) Lapatinib?

Yes. Every lot of O-De(3-fluorobenzyl) Lapatinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-De(3-fluorobenzyl) Lapatinib be shipped internationally?

Yes. We export O-De(3-fluorobenzyl) Lapatinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.