(-)-N-Deacetyl Colchicine

Name: (-)-N-Deacetyl Colchicine
Brand: Vaqora Chemicals
SKU: VQ-025075

About (-)-N-Deacetyl Colchicine

(-)-N-Deacetyl Colchicine is a metabolite or degradation product of Colchicine carrying the CAS registry number 3476-50-4. Its molecular formula is C20H23NO5 and its molecular weight is 357.4 g/mol. The IUPAC name is (7S)-7-amino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one. Common synonyms include (S)-N-Deacetyl Colchicine and N-Desacetyl Colchicine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Colchicine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (-)-N-Deacetyl Colchicine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Colchicine

View every impurity, metabolite and intermediate we list for Colchicine.

Colchicine impurities

Specifications & identifiers

Chemical identifiers
Product name	(-)-N-Deacetyl Colchicine
Catalogue No.	VQ-025075
CAS Number	3476-50-4
IUPAC name	(7S)-7-amino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one
Molecular formula	C₂₀H₂₃NO₅
Molecular weight	357.4 g/mol
Exact mass	357.1576
Grade	Reference Standard
HSN code	38229090
InChIKey	HFPMXDMZJUJZBX-AWEZNQCLSA-N
SMILES	COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)N
PubChem CID	18991

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	1 / 6
TPSA	80 Å²
Synonyms	(S)-N-Deacetyl Colchicine, N-Desacetyl Colchicine, Deacetylcolchicine, Desacetylcolchicine, Trimethylcolchicinic acid methyl ether, (S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo(a)heptalen-9(5H)-one, (7S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo(a)heptalen-9(5H)-one, (7S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one, N-Desacetylcolchicine, Tmca methyl ether

Safety & hazard information (GHS)

Corrosive

Toxic

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H318Causes serious eye damage
H340May cause genetic defects

Precautionary statements: P203, P264, P264 + P265, P270, P280, P301 + P316, P305 + P354 + P338, P317, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (-)-N-Deacetyl Colchicine?

The CAS Registry Number of (-)-N-Deacetyl Colchicine is 3476-50-4. It is also known as (S)-N-Deacetyl Colchicine, N-Desacetyl Colchicine, Deacetylcolchicine.

What is the molecular formula and molecular weight of (-)-N-Deacetyl Colchicine?

(-)-N-Deacetyl Colchicine has the molecular formula C20H23NO5 and a molecular weight of 357.4 g/mol. Its IUPAC name is (7S)-7-amino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one.

What is (-)-N-Deacetyl Colchicine used for?

(-)-N-Deacetyl Colchicine is supplied as a characterised reference material related to Colchicine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (-)-N-Deacetyl Colchicine can I order?

We supply (-)-N-Deacetyl Colchicine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (-)-N-Deacetyl Colchicine?

Yes. Every lot of (-)-N-Deacetyl Colchicine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (-)-N-Deacetyl Colchicine be shipped internationally?

Yes. (-)-N-Deacetyl Colchicine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.