Colchicine EP Impurity A

Name: Colchicine EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-025074

About Colchicine EP Impurity A

Vaqora Chemicals supplies Colchicine EP Impurity A, a pharmacopeial impurity of Colchicine registered under CAS number 7411-12-3. Its molecular formula is C21H23NO6 and its molecular weight is 385.4 g/mol. Systematically, it is named N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide. Common synonyms include Colchicine - Impurity A and Gloriosine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Colchicine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Colchicine EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Colchicine

View every impurity, metabolite and intermediate we list for Colchicine.

Colchicine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Colchicine EP Impurity A
Catalogue No.	VQ-025074
CAS Number	7411-12-3
IUPAC name	N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide
Molecular formula	C₂₁H₂₃NO₆
Molecular weight	385.4 g/mol
Exact mass	385.1525
Grade	Reference Standard
HSN code	38229090
InChIKey	HDSXDWASQCHADG-HNNXBMFYSA-N
SMILES	COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC=O
PubChem CID	23890

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	1 / 6
TPSA	83.1 Å²
Synonyms	Colchicine - Impurity A, Gloriosine, N-Deacetyl-N-formylcolchicine, N-Formyldeacetylcolchicine, N-Deacetyl-N-formyl Colchicine, N-Formyldesacetylcolchicine, Formyldescaetylcolchicine, N-, N-Formyl-N-deacetylcolchicine, Formamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, Gloriosine (N-Deacetyl-N-formyl-colchicin), (S)-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)formamide

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H318Causes serious eye damage
H319Causes serious eye irritation
H330Fatal if inhaled
H340May cause genetic defects

Precautionary statements: P203, P260, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P318, P320, P321, P330, P337 + P317, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Colchicine EP Impurity A?

The CAS Registry Number of Colchicine EP Impurity A is 7411-12-3. It is also known as Colchicine - Impurity A, Gloriosine, N-Deacetyl-N-formylcolchicine.

What is the molecular formula and molecular weight of Colchicine EP Impurity A?

Colchicine EP Impurity A has the molecular formula C21H23NO6 and a molecular weight of 385.4 g/mol. Its IUPAC name is N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide.

What is Colchicine EP Impurity A used for?

Colchicine EP Impurity A is supplied as a characterised reference material related to Colchicine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Colchicine EP Impurity A can I order?

We supply Colchicine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Colchicine EP Impurity A?

Yes. Every lot of Colchicine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Colchicine EP Impurity A be shipped internationally?

Yes. Colchicine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.