Colchicine EP Impurity D

Name: Colchicine EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-022146

About Colchicine EP Impurity D

Vaqora Chemicals supplies Colchicine EP Impurity D, a pharmacopeial impurity of Colchicine registered under CAS number 477-29-2. The compound has the formula C27H33NO11, corresponding to a molecular weight of 547.5 g/mol. It is also known as Colchicoside or Thiocolchicoside EP Impurity D.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Colchicine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Colchicine EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Colchicine

View every impurity, metabolite and intermediate we list for Colchicine.

Colchicine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Colchicine EP Impurity D
Catalogue No.	VQ-022146
CAS Number	477-29-2
IUPAC name	N-[(7S)-1,2,10-trimethoxy-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Molecular formula	C₂₇H₃₃NO₁₁
Molecular weight	547.5 g/mol
Exact mass	547.2054
Grade	Reference Standard
HSN code	38229090
InChIKey	UXAFRQPVHYZDED-ZZEDUEFDSA-N
SMILES	CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O
PubChem CID	92763

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	5 / 11
TPSA	173 Å²
Synonyms	Colchicoside, Thiocolchicoside EP Impurity D, Colchicine EP Impurity D (Colchicoside), Thiocolchicoside Hydrate - Impurity D, Colchicine - Impurity D, 3-Demethylcolchicine glucoside

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Colchicine EP Impurity D?

The CAS Registry Number of Colchicine EP Impurity D is 477-29-2. It is also known as Colchicoside, Thiocolchicoside EP Impurity D, Colchicine EP Impurity D (Colchicoside).

What is the molecular formula and molecular weight of Colchicine EP Impurity D?

Colchicine EP Impurity D has the molecular formula C27H33NO11 and a molecular weight of 547.5 g/mol. Its IUPAC name is N-[(7S)-1,2,10-trimethoxy-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.

What is Colchicine EP Impurity D used for?

Colchicine EP Impurity D is supplied as a characterised reference material related to Colchicine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Colchicine EP Impurity D can I order?

We supply Colchicine EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Colchicine EP Impurity D?

Yes. Every lot of Colchicine EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Colchicine EP Impurity D be shipped internationally?

Yes. Colchicine EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.