N-Desmethyl Selumetinib

Name: N-Desmethyl Selumetinib
Brand: Vaqora Chemicals
SKU: VQ-033806

About N-Desmethyl Selumetinib

N-Desmethyl Selumetinib is a metabolite or degradation product of Selumetinib carrying the CAS registry number 606143-88-8. Formula C16H13BrClFN4O3, molecular weight 443.7 g/mol. The IUPAC name is 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3H-benzimidazole-5-carboxamide. It is also known as Selumetinib metabolite M8.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Selumetinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer N-Desmethyl Selumetinib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Selumetinib

View every impurity, metabolite and intermediate we list for Selumetinib.

Selumetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Selumetinib
Catalogue No.	VQ-033806
CAS Number	606143-88-8
IUPAC name	6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3H-benzimidazole-5-carboxamide
Molecular formula	C₁₆H₁₃BrClFN₄O₃
Molecular weight	443.7 g/mol
Exact mass	441.9844
Grade	Reference Standard
HSN code	38229090
InChIKey	UBEOBEUUUKHITB-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1Br)Cl)NC2=C(C3=C(C=C2C(=O)NOCCO)NC=N3)F
PubChem CID	10238358

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	4 / 6
TPSA	99.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Selumetinib?

The CAS Registry Number of N-Desmethyl Selumetinib is 606143-88-8. It is also known as Selumetinib metabolite M8.

What is the molecular formula and molecular weight of N-Desmethyl Selumetinib?

N-Desmethyl Selumetinib has the molecular formula C16H13BrClFN4O3 and a molecular weight of 443.7 g/mol. Its IUPAC name is 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3H-benzimidazole-5-carboxamide.

What is N-Desmethyl Selumetinib used for?

N-Desmethyl Selumetinib is supplied as a characterised reference material related to Selumetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Selumetinib can I order?

We supply N-Desmethyl Selumetinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Selumetinib?

Yes. Every lot of N-Desmethyl Selumetinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Selumetinib be shipped internationally?

Yes. We export N-Desmethyl Selumetinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.