Selumetinib

Name: Selumetinib
Brand: Vaqora Chemicals
SKU: VQ-007748

About Selumetinib

Selumetinib (CAS 606143-52-6) is a high-purity reference standard of Selumetinib offered by Vaqora Chemicals. Formula C17H15BrClFN4O3, molecular weight 457.7 g/mol. Systematically, it is named 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide. It is also known as AZD 6244 or AZD-6244.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Selumetinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Selumetinib

View every impurity, metabolite and intermediate we list for Selumetinib.

Selumetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Selumetinib
Catalogue No.	VQ-007748
CAS Number	606143-52-6
IUPAC name	6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
Molecular formula	C₁₇H₁₅BrClFN₄O₃
Molecular weight	457.7 g/mol
Exact mass	456
Grade	Reference Standard
HSN code	38229090
InChIKey	CYOHGALHFOKKQC-UHFFFAOYSA-N
SMILES	CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
PubChem CID	10127622

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	3 / 6
TPSA	88.4 Å²
Synonyms	AZD 6244, AZD-6244, ARRY-886, MEK inhibitor AZD6244, Selumetinib (AZD6244), AZD6244 (Selumetinib), EX-A020, C17H15BrClFN4O3, 3EW, Selumetinib (USAN/INN), SelumetinibAZD6244, ARRY-142886, AZD6244,Selumetinib, ARRY-142886

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H318Causes serious eye damage
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P261, P264, P264 + P265, P270, P272, P273, P280, P301 + P317, P302 + P352, P305 + P354 + P338, P317, P318, P319, P321, P330, P333 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Selumetinib?

The CAS Registry Number of Selumetinib is 606143-52-6. It is also known as AZD 6244, AZD-6244, ARRY-886.

What is the molecular formula and molecular weight of Selumetinib?

Selumetinib has the molecular formula C17H15BrClFN4O3 and a molecular weight of 457.7 g/mol. Its IUPAC name is 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide.

What is Selumetinib used for?

Selumetinib is supplied as a characterised reference material related to Selumetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Selumetinib can I order?

We supply Selumetinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Selumetinib?

Yes. Every lot of Selumetinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Selumetinib be shipped internationally?

Yes. Selumetinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.