Selumetinib Nitroso Impurity-4

Name: Selumetinib Nitroso Impurity-4
Brand: Vaqora Chemicals
SKU: VQ-007046

About Selumetinib Nitroso Impurity-4

Selumetinib Nitroso Impurity-4 is a nitrosamine impurity of Selumetinib offered by Vaqora Chemicals at a purity of 92%. Its molecular formula is C17H14BrClFN5O4 and its molecular weight is 486.7 g/mol. The IUPAC name is 6-(4-bromo-2-chloro-N-nitrosoanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide. It is also known as N-Nitroso Selumetinib or Selumetinib Impurity 23.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Selumetinib, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Selumetinib Nitroso Impurity-4 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Selumetinib

View every impurity, metabolite and intermediate we list for Selumetinib.

Selumetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Selumetinib Nitroso Impurity-4
Catalogue No.	VQ-007046
IUPAC name	6-(4-bromo-2-chloro-N-nitrosoanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
Molecular formula	C₁₇H₁₄BrClFN₅O₄
Molecular weight	486.7 g/mol
Exact mass	484.9902
Grade	Reference Standard
Purity / assay	92%
HSN code	38229090
InChIKey	MTGDXCDMQLOCKG-UHFFFAOYSA-N
SMILES	CN1C=NC2=C1C=C(C(=C2F)N(C3=C(C=C(C=C3)Br)Cl)N=O)C(=O)NOCCO
PubChem CID	169444677

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 8
TPSA	109 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the molecular formula and molecular weight of Selumetinib Nitroso Impurity-4?

Selumetinib Nitroso Impurity-4 has the molecular formula C17H14BrClFN5O4 and a molecular weight of 486.7 g/mol. Its IUPAC name is 6-(4-bromo-2-chloro-N-nitrosoanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide.

What is Selumetinib Nitroso Impurity-4 used for?

Selumetinib Nitroso Impurity-4 is supplied as a characterised reference material related to Selumetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Selumetinib Nitroso Impurity-4 can I order?

We supply Selumetinib Nitroso Impurity-4 in Reference Standard (92%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Selumetinib Nitroso Impurity-4?

Yes. Every lot of Selumetinib Nitroso Impurity-4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Selumetinib Nitroso Impurity-4 be shipped internationally?

Yes. We export Selumetinib Nitroso Impurity-4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.