Nintedanib E-Isomer

Name: Nintedanib E-Isomer
Brand: Vaqora Chemicals
SKU: VQ-026920

About Nintedanib E-Isomer

Nintedanib E-Isomer (CAS 1160294-26-7) is an impurity of Nintedanib offered by Vaqora Chemicals. The compound has the formula C31H33N5O4, corresponding to a molecular weight of 539.6 g/mol. It is also known as BIBF-1120 or BIBF 1120.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Nintedanib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nintedanib E-Isomer in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib E-Isomer
Catalogue No.	VQ-026920
CAS Number	1160294-26-7
IUPAC name	methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
Molecular formula	C₃₁H₃₃N₅O₄
Molecular weight	539.6 g/mol
Exact mass	539.2533
Grade	Reference Standard
HSN code	38229090
InChIKey	CPMDPSXJELVGJG-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
PubChem CID	135423438

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 7
TPSA	101 Å²
Synonyms	BIBF-1120, BIBF 1120, Nintedanib (BIBF 1120), (E)-Nintedanib, BIBF1120,Vargatef, Nintedanib (free base), BIBF1120 (Vargatef), BIBF 1120 (Nintedanib), US10669235, Nintedanib, Nintedanib - Bio-X trade mark, EX-A341

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib E-Isomer?

The CAS Registry Number of Nintedanib E-Isomer is 1160294-26-7. It is also known as BIBF-1120, BIBF 1120, Nintedanib (BIBF 1120).

What is the molecular formula and molecular weight of Nintedanib E-Isomer?

Nintedanib E-Isomer has the molecular formula C31H33N5O4 and a molecular weight of 539.6 g/mol. Its IUPAC name is methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate.

What is Nintedanib E-Isomer used for?

Nintedanib E-Isomer is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib E-Isomer can I order?

We supply Nintedanib E-Isomer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib E-Isomer?

Yes. Every lot of Nintedanib E-Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib E-Isomer be shipped internationally?

Yes. We export Nintedanib E-Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.