N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitr… 1139453-98-7

Name: N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Brand: Vaqora Chemicals
SKU: VQ-026921

About N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide

Vaqora Chemicals supplies N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide, an impurity of Nintedanib registered under CAS number 1139453-98-7. Formula C14H20N4O3, molecular weight 292.33 g/mol. Common synonyms include Nintedanib-003 and Nintedanib Intermediate 1.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Nintedanib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Catalogue No.	VQ-026921
CAS Number	1139453-98-7
IUPAC name	N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Molecular formula	C₁₄H₂₀N₄O₃
Molecular weight	292.33 g/mol
Exact mass	292.1535
Grade	Reference Standard
HSN code	38229090
InChIKey	LSQRHFSGOUDQDS-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)[N+](=O)[O-]
PubChem CID	23507600

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	0 / 5
TPSA	72.6 Å²
Synonyms	N,4-Dimethyl-N-(4-nitrophenyl)-1-piperazineacetamide, 1-Piperazineacetamide, N,4-dimethyl-N-(4-nitrophenyl)-, N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide, Nintedanib-003, Nintedanib Intermediate 1

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide?

The CAS Registry Number of N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide is 1139453-98-7. It is also known as N,4-Dimethyl-N-(4-nitrophenyl)-1-piperazineacetamide, 1-Piperazineacetamide, N,4-dimethyl-N-(4-nitrophenyl)-, N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide.

What is the molecular formula and molecular weight of N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide?

N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide has the molecular formula C14H20N4O3 and a molecular weight of 292.33 g/mol. Its IUPAC name is N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide.

What is N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide used for?

N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide can I order?

We supply N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide?

Yes. Every lot of N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide be shipped internationally?

Yes. N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.