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Nitrosamine ImpuritiesReference StandardAvailable on request

N-Nitroso-L-Hydroxyproline

Synonyms: N-Nitroso (2S,4R)-4-Hydroxypyrrolidin-2-Carboxylic acid · N-Nitrosohydroxyproline · (4R)-4-hydroxy-1-nitroso-L-proline · trans-4-Hydroxy-1-nitroso-L-proline

CAS No.30310-80-6
FormulaC5H8N2O4
Mol. weight160.13
Catalogue No.VQ-027126
PurityReference Standard
HSN38229090

N-Nitroso-L-Hydroxyproline (CAS 30310-80-6) – nitrosamine impurity reference standard. C5H8N2O4, MW 160.13. Vaqora Chemicals: COA, global shipping.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About N-Nitroso-L-Hydroxyproline

Vaqora Chemicals supplies N-Nitroso-L-Hydroxyproline, a nitrosamine impurity of Hydroxyproline registered under CAS number 30310-80-6. Its molecular formula is C5H8N2O4 and its molecular weight is 160.13 g/mol. Systematically, it is named (2S,4R)-4-hydroxy-1-nitrosopyrrolidine-2-carboxylic acid. It is also known as N-Nitrosohydroxyproline or (4R)-4-hydroxy-1-nitroso-L-proline.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Hydroxyproline, method validation (AMV) and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitroso-L-Hydroxyproline in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

  • Nitrosamine risk assessment
  • Trace LC-MS/MS quantitation
  • Method validation (AMV)
  • Regulatory submissions

Industries

Related to Hydroxyproline

View every impurity, metabolite and intermediate we list for Hydroxyproline.

Hydroxyproline impurities

Specifications & identifiers

Chemical identifiers
Product nameN-Nitroso-L-Hydroxyproline
Catalogue No.VQ-027126
CAS Number30310-80-6
IUPAC name(2S,4R)-4-hydroxy-1-nitrosopyrrolidine-2-carboxylic acid
Molecular formulaC5H8N2O4
Molecular weight160.13 g/mol
Exact mass160.0484
GradeReference Standard
HSN code38229090
InChIKeyABVBOWJCKJGCJM-DMTCNVIQSA-N
SMILESC1[C@H](CN([C@@H]1C(=O)O)N=O)O
PubChem CID61873
Physical properties
Physical formSolid
LogP (XLogP3)-0.7
H-bond donors / acceptors2 / 6
TPSA90.2 Ų
SynonymsN-Nitroso (2S,4R)-4-Hydroxypyrrolidin-2-Carboxylic acid, N-Nitrosohydroxyproline, (4R)-4-hydroxy-1-nitroso-L-proline, trans-4-Hydroxy-1-nitroso-L-proline, Proline, 4-hydroxy-1-nitroso-, L-, 4-Hydroxy-1-nitroso-L-proline, Nitrosohydroxyproline, L-Proline, 4-hydroxy-1-nitroso-, (4R)-, (2S,4R)-4-hydroxy-1-nitroso-pyrrolidine-2-carboxylic acid

Documents

Frequently asked questions

What is the CAS number of N-Nitroso-L-Hydroxyproline?

The CAS Registry Number of N-Nitroso-L-Hydroxyproline is 30310-80-6. It is also known as N-Nitroso (2S,4R)-4-Hydroxypyrrolidin-2-Carboxylic acid, N-Nitrosohydroxyproline, (4R)-4-hydroxy-1-nitroso-L-proline.

What is the molecular formula and molecular weight of N-Nitroso-L-Hydroxyproline?

N-Nitroso-L-Hydroxyproline has the molecular formula C5H8N2O4 and a molecular weight of 160.13 g/mol. Its IUPAC name is (2S,4R)-4-hydroxy-1-nitrosopyrrolidine-2-carboxylic acid.

What is N-Nitroso-L-Hydroxyproline used for?

N-Nitroso-L-Hydroxyproline is supplied as a characterised reference material related to Hydroxyproline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-L-Hydroxyproline can I order?

We supply N-Nitroso-L-Hydroxyproline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-L-Hydroxyproline?

Yes. Every lot of N-Nitroso-L-Hydroxyproline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-L-Hydroxyproline be shipped internationally?

Yes. We export N-Nitroso-L-Hydroxyproline worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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