Naloxone EP Impurity G

Name: Naloxone EP Impurity G
Brand: Vaqora Chemicals
SKU: VQ-043240

About Naloxone EP Impurity G

Naloxone EP Impurity G is a pharmacopeial impurity of Naloxon carrying the CAS registry number 70866-64-7. With the molecular formula C20H23NO4, it has a molar mass of 341.4 g/mol. Common synonyms include Naloxone 3-methyl Ether and Naloxone Hydrochloride EP Impurity G.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Naloxon to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Naloxone EP Impurity G in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Naloxon

View every impurity, metabolite and intermediate we list for Naloxon.

Naloxon impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Naloxone EP Impurity G
Catalogue No.	VQ-043240
CAS Number	70866-64-7
IUPAC name	(4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formula	C₂₀H₂₃NO₄
Molecular weight	341.4 g/mol
Exact mass	341.1627
Grade	Reference Standard
HSN code	38229090
InChIKey	SSVPTPGFVKXIRF-XFWGSAIBSA-N
SMILES	COC1=C2C3=C(C[C@@H]4[C@]5([C@]3(CCN4CC=C)[C@@H](O2)C(=O)CC5)O)C=C1
PubChem CID	11056967

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 5
TPSA	59 Å²
Synonyms	Naloxone 3-methyl Ether, Naloxone Hydrochloride EP Impurity G, Naloxone Hydrochloride - Impurity G, 3-O-Methylnaloxone, N-Allyldihydro-14-hydroxynorcodeinone, (5alpha)-4,5-Epoxy-14-hydroxy-3-methoxy-17-(2-propen-1-yl)morphinan-6-one, Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-(2-propen-1-yl)-, (5alpha)-, RAM-303, 7,8-Dihydro-N-allyl-14-hydroxynorcodeinone, Norcodeinone, 7,8-dihydro-N-allyl-14-hydroxy-, 17-Allyl-4,5-alpha-epoxy-14-hydroxy-3-methoxymorphinan-6-one, Morphinan-6-one, 17-allyl-4,5-alpha-epoxy-14-hydroxy-3-methoxy-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naloxone EP Impurity G?

The CAS Registry Number of Naloxone EP Impurity G is 70866-64-7. It is also known as Naloxone 3-methyl Ether, Naloxone Hydrochloride EP Impurity G, Naloxone Hydrochloride - Impurity G.

What is the molecular formula and molecular weight of Naloxone EP Impurity G?

Naloxone EP Impurity G has the molecular formula C20H23NO4 and a molecular weight of 341.4 g/mol. Its IUPAC name is (4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.

What is Naloxone EP Impurity G used for?

Naloxone EP Impurity G is supplied as a characterised reference material related to Naloxon. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naloxone EP Impurity G can I order?

We supply Naloxone EP Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naloxone EP Impurity G?

Yes. Every lot of Naloxone EP Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naloxone EP Impurity G be shipped internationally?

Yes. We export Naloxone EP Impurity G worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.