NAP006-06 (Z isomer)

Name: NAP006-06 (Z isomer)
Brand: Vaqora Chemicals
SKU: VQ-033718

About NAP006-06 (Z isomer)

Listed under CAS 1361408-16-3, NAP006-06 (Z isomer) is an impurity of Sacubitril available from Vaqora Chemicals. The compound has the formula C23H27NO4, corresponding to a molecular weight of 381.5 g/mol. Its systematic (IUPAC) name is (Z,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pent-2-enoic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Sacubitril to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	NAP006-06 (Z isomer)
Catalogue No.	VQ-033718
CAS Number	1361408-16-3
IUPAC name	(Z,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pent-2-enoic acid
Molecular formula	C₂₃H₂₇NO₄
Molecular weight	381.5 g/mol
Exact mass	381.194
Grade	Reference Standard
HSN code	38229090
InChIKey	JXTNUXJSXXIIFE-HZMYXVCSSA-N
SMILES	C/C(=C/[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)OC(C)(C)C)/C(=O)O
PubChem CID	56847899

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of NAP006-06 (Z isomer)?

The CAS Registry Number of NAP006-06 (Z isomer) is 1361408-16-3. It is also known as (R,Z)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid, (Z)-(R)-5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpent-2-enoic acid.

What is the molecular formula and molecular weight of NAP006-06 (Z isomer)?

NAP006-06 (Z isomer) has the molecular formula C23H27NO4 and a molecular weight of 381.5 g/mol. Its IUPAC name is (Z,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pent-2-enoic acid.

What is NAP006-06 (Z isomer) used for?

NAP006-06 (Z isomer) is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of NAP006-06 (Z isomer) can I order?

We supply NAP006-06 (Z isomer) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with NAP006-06 (Z isomer)?

Yes. Every lot of NAP006-06 (Z isomer) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can NAP006-06 (Z isomer) be shipped internationally?

Yes. We export NAP006-06 (Z isomer) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.