Nintedanib Impurity A

Name: Nintedanib Impurity A
Brand: Vaqora Chemicals
SKU: VQ-005378

About Nintedanib Impurity A

Listed under CAS 2734676-68-5, Nintedanib Impurity A is an impurity of Nintedanib available from Vaqora Chemicals, specified at 95% purity. Its molecular formula is C31H33N5O6 and its molecular weight is 571.6 g/mol. Alternative names: Nintedanib Piperazinyl N,N'-Dioxide and Intedanib Piperazinyl N,N'-Dioxide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Nintedanib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib Impurity A
Catalogue No.	VQ-005378
CAS Number	2734676-68-5
IUPAC name	methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methyl-1,4-dioxidopiperazine-1,4-diium-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
Molecular formula	C₃₁H₃₃N₅O₆
Molecular weight	571.6 g/mol
Exact mass	571.2431
Grade	Reference Standard
Purity / assay	95%
HSN code	38229090
InChIKey	UGEGJAQWOFSWLP-UHFFFAOYSA-N
SMILES	CN(C1=CC=C(C=C1)N=C(C2=CC=CC=C2)C3=C(NC4=C3C=CC(=C4)C(=O)OC)O)C(=O)C[N+]5(CC[N+](CC5)(C)[O-])[O-]
PubChem CID	169442487

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	2 / 7
TPSA	131 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib Impurity A?

The CAS Registry Number of Nintedanib Impurity A is 2734676-68-5. It is also known as Nintedanib Piperazinyl N,N'-Dioxide, Intedanib Piperazinyl N,N'-Dioxide, Nintedanib Impurity 51.

What is the molecular formula and molecular weight of Nintedanib Impurity A?

Nintedanib Impurity A has the molecular formula C31H33N5O6 and a molecular weight of 571.6 g/mol. Its IUPAC name is methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methyl-1,4-dioxidopiperazine-1,4-diium-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate.

What is Nintedanib Impurity A used for?

Nintedanib Impurity A is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib Impurity A can I order?

We supply Nintedanib Impurity A in Reference Standard (95%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib Impurity A?

Yes. Every lot of Nintedanib Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib Impurity A be shipped internationally?

Yes. We export Nintedanib Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.