Nintedanib Impurity E (n-1)

Name: Nintedanib Impurity E (n-1)
Brand: Vaqora Chemicals
SKU: VQ-005383

About Nintedanib Impurity E (n-1)

Nintedanib Impurity E (n-1) is an impurity of Nintedanib carrying the CAS registry number 1253769-13-9 at a purity of 94%. The compound has the formula C20H17NO5, corresponding to a molecular weight of 351.4 g/mol. The IUPAC name is methyl (3Z)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Nintedanib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Nintedanib Impurity E (n-1) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib Impurity E (n-1)
Catalogue No.	VQ-005383
CAS Number	1253769-13-9
IUPAC name	methyl (3Z)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate
Molecular formula	C₂₀H₁₇NO₅
Molecular weight	351.4 g/mol
Exact mass	351.1107
Grade	Reference Standard
Purity / assay	94%
HSN code	38229090
InChIKey	IAELOHNWFVWCNO-ZCXUNETKSA-N
SMILES	CC(=O)N1C2=C(C=CC(=C2)C(=O)OC)/C(=C(\C3=CC=CC=C3)/OC)/C1=O
PubChem CID	118430741

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 5
TPSA	72.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib Impurity E (n-1)?

The CAS Registry Number of Nintedanib Impurity E (n-1) is 1253769-13-9. It is also known as Methyl (Z)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl (3Z)-1-acetyl-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylate, (Z)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate.

What is the molecular formula and molecular weight of Nintedanib Impurity E (n-1)?

Nintedanib Impurity E (n-1) has the molecular formula C20H17NO5 and a molecular weight of 351.4 g/mol. Its IUPAC name is methyl (3Z)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate.

What is Nintedanib Impurity E (n-1) used for?

Nintedanib Impurity E (n-1) is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib Impurity E (n-1) can I order?

We supply Nintedanib Impurity E (n-1) in Reference Standard (94%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib Impurity E (n-1)?

Yes. Every lot of Nintedanib Impurity E (n-1) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib Impurity E (n-1) be shipped internationally?

Yes. We export Nintedanib Impurity E (n-1) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.