Nintedanib Nitroso Impurity 2 (Stage-II)

Name: Nintedanib Nitroso Impurity 2 (Stage-II)
Brand: Vaqora Chemicals
SKU: VQ-007010

About Nintedanib Nitroso Impurity 2 (Stage-II)

Vaqora Chemicals supplies Nintedanib Nitroso Impurity 2 (Stage-II), a nitrosamine impurity of Nintedanib registered under CAS number 2037385-84-3, specified at 97% purity. Formula C13H19ClN4O3, molecular weight 314.77 g/mol. Systematically, it is named N-methyl-N-(4-nitrophenyl)-2-piperazin-1-ylacetamide. Hydrochloride. It is also known as Nintedanib Impurity 10.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Nintedanib, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nintedanib Nitroso Impurity 2 (Stage-II) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib Nitroso Impurity 2 (Stage-II)
Catalogue No.	VQ-007010
CAS Number	2037385-84-3
Other CAS	1038972-16-5
IUPAC name	N-methyl-N-(4-nitrophenyl)-2-piperazin-1-ylacetamide;hydrochloride
Molecular formula	C₁₃H₁₉ClN₄O₃
Molecular weight	314.77 g/mol
Exact mass	314.1146
Grade	Reference Standard
Purity / assay	97%
HSN code	38229090
InChIKey	BEWYKGJKRFUIJP-UHFFFAOYSA-N
SMILES	CN(C1=CC=C(C=C1)[N+](=O)[O-])C(=O)CN2CCNCC2.Cl
PubChem CID	168010480

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 5
TPSA	81.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib Nitroso Impurity 2 (Stage-II)?

The CAS Registry Number of Nintedanib Nitroso Impurity 2 (Stage-II) is 2037385-84-3. It is also known as N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide hydrochloride, Nintedanib Impurity 10.

What is the molecular formula and molecular weight of Nintedanib Nitroso Impurity 2 (Stage-II)?

Nintedanib Nitroso Impurity 2 (Stage-II) has the molecular formula C13H19ClN4O3 and a molecular weight of 314.77 g/mol.

What is Nintedanib Nitroso Impurity 2 (Stage-II) used for?

Nintedanib Nitroso Impurity 2 (Stage-II) is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib Nitroso Impurity 2 (Stage-II) can I order?

We supply Nintedanib Nitroso Impurity 2 (Stage-II) in Reference Standard (97%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib Nitroso Impurity 2 (Stage-II)?

Yes. Every lot of Nintedanib Nitroso Impurity 2 (Stage-II) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib Nitroso Impurity 2 (Stage-II) be shipped internationally?

Yes. We export Nintedanib Nitroso Impurity 2 (Stage-II) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.