Nisoldipine EP Impurity B

Name: Nisoldipine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-006538

About Nisoldipine EP Impurity B

Nisoldipine EP Impurity B (CAS 21881-78-7) is a pharmacopeial impurity of Nisoldipine offered by Vaqora Chemicals. The compound has the formula C21H26N2O6, corresponding to a molecular weight of 402.4 g/mol. Systematically, it is named dipropan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Common synonyms include Nimodipine EP Impurity B and Nimodipine impurity B.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Nisoldipine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nisoldipine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nisoldipine

View every impurity, metabolite and intermediate we list for Nisoldipine.

Nisoldipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nisoldipine EP Impurity B
Catalogue No.	VQ-006538
CAS Number	21881-78-7
IUPAC name	dipropan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Molecular formula	C₂₁H₂₆N₂O₆
Molecular weight	402.4 g/mol
Exact mass	402.1791
Grade	Reference Standard
HSN code	38229090
InChIKey	UPOXKUKUWZYRQV-UHFFFAOYSA-N
SMILES	CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC(C)C
PubChem CID	4346554

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	1 / 7
TPSA	110 Å²
Synonyms	Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, Bis(1-methylethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine, Nimodipine EP Impurity B, Nimodipine impurity B, 3,5-bis(propan-2-yl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, Nimodipine EP Imp B, Nimodipine Impurity B Control, (RS)-Di-iso-propyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate, (RS)-Di-isopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate, 3,5-diisopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nisoldipine EP Impurity B?

The CAS Registry Number of Nisoldipine EP Impurity B is 21881-78-7. It is also known as Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, Bis(1-methylethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine.

What is the molecular formula and molecular weight of Nisoldipine EP Impurity B?

Nisoldipine EP Impurity B has the molecular formula C21H26N2O6 and a molecular weight of 402.4 g/mol. Its IUPAC name is dipropan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

What is Nisoldipine EP Impurity B used for?

Nisoldipine EP Impurity B is supplied as a characterised reference material related to Nisoldipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nisoldipine EP Impurity B can I order?

We supply Nisoldipine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nisoldipine EP Impurity B?

Yes. Every lot of Nisoldipine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nisoldipine EP Impurity B be shipped internationally?

Yes. Nisoldipine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.