Nisoldipine Impurity A

Name: Nisoldipine Impurity A
Brand: Vaqora Chemicals
SKU: VQ-005391

About Nisoldipine Impurity A

Nisoldipine Impurity A (CAS 21829-25-4) is an impurity of Nisoldipine offered by Vaqora Chemicals. Formula C17H18N2O6, molecular weight 346.3 g/mol. Its systematic (IUPAC) name is dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Common synonyms include Nifedipine and Adalat.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Nisoldipine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nisoldipine

View every impurity, metabolite and intermediate we list for Nisoldipine.

Nisoldipine impurities

Specifications & identifiers

Chemical identifiers
Product name	Nisoldipine Impurity A
Catalogue No.	VQ-005391
CAS Number	21829-25-4
IUPAC name	dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Molecular formula	C₁₇H₁₈N₂O₆
Molecular weight	346.3 g/mol
Exact mass	346.1165
Grade	Reference Standard
HSN code	38229090
InChIKey	HYIMSNHJOBLJNT-UHFFFAOYSA-N
SMILES	CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
PubChem CID	4485

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 7
TPSA	110 Å²
Synonyms	1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester, 2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine, 2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester, 2,6-Dimethyl-4-(o-nitrophenyl)-3,5-dimethoxycarbonyl-1,4-dihydropyridine, 3,5-Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, 4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine, Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate, Nifedipine, Adalat, Adapine, Adapress, Alat

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 21829-25-4

IP/BP/USP

Nifedipine

CAS: 21829-25-4
Formula: C₁₇H₁₈N₂O₆
MW: 346.3 g/mol

VQ-004101

Frequently asked questions

What is the CAS number of Nisoldipine Impurity A?

The CAS Registry Number of Nisoldipine Impurity A is 21829-25-4. It is also known as 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester, 2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine, 2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester.

What is the molecular formula and molecular weight of Nisoldipine Impurity A?

Nisoldipine Impurity A has the molecular formula C17H18N2O6 and a molecular weight of 346.3 g/mol. Its IUPAC name is dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

What is Nisoldipine Impurity A used for?

Nisoldipine Impurity A is supplied as a characterised reference material related to Nisoldipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nisoldipine Impurity A can I order?

We supply Nisoldipine Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nisoldipine Impurity A?

Yes. Every lot of Nisoldipine Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nisoldipine Impurity A be shipped internationally?

Yes. Nisoldipine Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.