Nifedipine

Name: Nifedipine
Brand: Vaqora Chemicals
SKU: VQ-004101

About Nifedipine

Nifedipine (CAS 21829-25-4) is a cardiovascular API offered by Vaqora Chemicals (IP/BP/USP grade). The compound has the formula C17H18N2O6, corresponding to a molecular weight of 346.3 g/mol. The IUPAC name is dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. It is also known as Procardia XL or Adalat CC.

It is supplied as a yellow crystalline solid. Keep the container tightly sealed and store it in a cool, dry area. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This API belongs to our cardiovascular and antihypertensive APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Typical end-use sectors are pharmaceutical manufacturing.

Vaqora Chemicals supplies Nifedipine in 1 kg, 5 kg and 25 kg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Nifedipine

View every impurity, metabolite and intermediate we list for Nifedipine.

Nifedipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nifedipine
Catalogue No.	VQ-004101
CAS Number	21829-25-4
IUPAC name	dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Molecular formula	C₁₇H₁₈N₂O₆
Molecular weight	346.3 g/mol
Exact mass	346.1165
Grade	IP/BP/USP
HSN code	2933
InChIKey	HYIMSNHJOBLJNT-UHFFFAOYSA-N
SMILES	CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
PubChem CID	4485

Physical properties
Physical form	Crystalline
Appearance	Yellow crystalline solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 7
TPSA	110 Å²
Synonyms	Procardia XL, Adalat CC, Fenihidine, Bay-a-1040, Afeditab CR, Adipine XL, Nifedical, BAY A 1040, 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester, Nifensar XL, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester, Nifedical XL

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 21829-25-4

Reference Standard

Nisoldipine Impurity A

CAS: 21829-25-4
Formula: C₁₇H₁₈N₂O₆
MW: 346.3 g/mol

VQ-005391

Frequently asked questions

What is the CAS number of Nifedipine?

The CAS Registry Number of Nifedipine is 21829-25-4. It is also known as Procardia XL, Adalat CC, Fenihidine.

What is the molecular formula and molecular weight of Nifedipine?

Nifedipine has the molecular formula C17H18N2O6 and a molecular weight of 346.3 g/mol. Its IUPAC name is dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

What is Nifedipine used for?

Nifedipine is supplied as a characterised reference material related to Nifedipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nifedipine can I order?

We supply Nifedipine in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nifedipine?

Yes. Every lot of Nifedipine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nifedipine be shipped internationally?

Yes. Nifedipine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.