O-Methyl Dolutegravir

Name: O-Methyl Dolutegravir
Brand: Vaqora Chemicals
SKU: VQ-013674

About O-Methyl Dolutegravir

O-Methyl Dolutegravir is a process intermediate or related compound of Dolutegravir carrying the CAS registry number 1335210-35-9, specified at 94.28% purity. Its molecular formula is C21H21F2N3O5 and its molecular weight is 433.4 g/mol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Dolutegravir, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dolutegravir

View every impurity, metabolite and intermediate we list for Dolutegravir.

Dolutegravir impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Methyl Dolutegravir
Catalogue No.	VQ-013674
CAS Number	1335210-35-9
IUPAC name	(3S,7R)-N-[(2,4-difluorophenyl)methyl]-11-methoxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide
Molecular formula	C₂₁H₂₁F₂N₃O₅
Molecular weight	433.4 g/mol
Exact mass	433.1449
Grade	Reference Standard
Purity / assay	94.28%
HSN code	2933
InChIKey	MOSMLVZNRGURDI-BZNIZROVSA-N
SMILES	C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)OC
PubChem CID	53469002

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 8
TPSA	88.2 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P233, P260, P261, P264, P264 + P265, P270, P271, P272, P273, P280, P284, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P342 + P316

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Methyl Dolutegravir?

The CAS Registry Number of O-Methyl Dolutegravir is 1335210-35-9.

What is the molecular formula and molecular weight of O-Methyl Dolutegravir?

O-Methyl Dolutegravir has the molecular formula C21H21F2N3O5 and a molecular weight of 433.4 g/mol. Its IUPAC name is (3S,7R)-N-[(2,4-difluorophenyl)methyl]-11-methoxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide.

What is O-Methyl Dolutegravir used for?

O-Methyl Dolutegravir is supplied as a characterised reference material related to Dolutegravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Methyl Dolutegravir can I order?

We supply O-Methyl Dolutegravir in Reference Standard (94.28%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Methyl Dolutegravir?

Yes. Every lot of O-Methyl Dolutegravir is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Methyl Dolutegravir be shipped internationally?

Yes. O-Methyl Dolutegravir is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.