Paclitaxel EP Impurity E

Name: Paclitaxel EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-023453

About Paclitaxel EP Impurity E

Vaqora Chemicals supplies Paclitaxel EP Impurity E, a pharmacopeial impurity of Paclitaxel registered under CAS number 105454-04-4. With the molecular formula C47H51NO14, it has a molar mass of 853.9 g/mol. Common synonyms include 7-Epi-Paclitaxel and Paclitaxel - Impurity E.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Paclitaxel impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Paclitaxel EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Paclitaxel

View every impurity, metabolite and intermediate we list for Paclitaxel.

Paclitaxel impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Paclitaxel EP Impurity E
Catalogue No.	VQ-023453
CAS Number	105454-04-4
IUPAC name	[(1S,2S,3R,4S,7R,9R,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Molecular formula	C₄₇H₅₁NO₁₄
Molecular weight	853.9 g/mol
Exact mass	853.331
Grade	Reference Standard
HSN code	38229090
InChIKey	RCINICONZNJXQF-LYTKHFMESA-N
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
PubChem CID	184492

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	4 / 14
TPSA	221 Å²
Synonyms	7-Epi-Paclitaxel, Paclitaxel - Impurity E, 7-Epitaxol, 7-epi-Taxol, Epitaxol, 7-Epipaclitaxel, 7-Epi Paclitaxel, Paclitaxel Impurity inverted exclamation marke (R):(7-Epi-Paclitaxel)

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H340May cause genetic defects
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P233, P260, P261, P264, P264 + P265, P270, P271, P272, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P333 + P317, P342 + P316, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Paclitaxel EP Impurity E?

The CAS Registry Number of Paclitaxel EP Impurity E is 105454-04-4. It is also known as 7-Epi-Paclitaxel, Paclitaxel - Impurity E, 7-Epitaxol.

What is the molecular formula and molecular weight of Paclitaxel EP Impurity E?

Paclitaxel EP Impurity E has the molecular formula C47H51NO14 and a molecular weight of 853.9 g/mol.

What is Paclitaxel EP Impurity E used for?

Paclitaxel EP Impurity E is supplied as a characterised reference material related to Paclitaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Paclitaxel EP Impurity E can I order?

We supply Paclitaxel EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Paclitaxel EP Impurity E?

Yes. Every lot of Paclitaxel EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Paclitaxel EP Impurity E be shipped internationally?

Yes. Paclitaxel EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.